ID W4LZX1_9BACT Unreviewed; 286 AA.
AC W4LZX1;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Polymerase beta nucleotidyltransferase domain-containing protein {ECO:0000259|Pfam:PF18765};
DE Flags: Fragment;
GN ORFNames=ETSY2_33370 {ECO:0000313|EMBL:ETX03475.1};
OS Candidatus Entotheonella gemina.
OC Bacteria; Nitrospinae/Tectomicrobia group; Candidatus Tectomicrobia;
OC Entotheonella.
OX NCBI_TaxID=1429439 {ECO:0000313|EMBL:ETX03475.1, ECO:0000313|Proteomes:UP000019140};
RN [1] {ECO:0000313|EMBL:ETX03475.1, ECO:0000313|Proteomes:UP000019140}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TSY2 {ECO:0000313|Proteomes:UP000019140};
RX PubMed=24476823; DOI=10.1038/nature12959;
RA Wilson M.C., Mori T., Ruckert C., Uria A.R., Helf M.J., Takada K.,
RA Gernert C., Steffens U.A., Heycke N., Schmitt S., Rinke C., Helfrich E.J.,
RA Brachmann A.O., Gurgui C., Wakimoto T., Kracht M., Crusemann M.,
RA Hentschel U., Abe I., Matsunaga S., Kalinowski J., Takeyama H., Piel J.;
RT "An environmental bacterial taxon with a large and distinct metabolic
RT repertoire.";
RL Nature 506:58-62(2014).
CC -!- SIMILARITY: Belongs to the HepT RNase toxin family.
CC {ECO:0000256|ARBA:ARBA00024207}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETX03475.1}.
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DR EMBL; AZHX01001428; ETX03475.1; -; Genomic_DNA.
DR AlphaFoldDB; W4LZX1; -.
DR HOGENOM; CLU_971461_0_0_7; -.
DR Proteomes; UP000019140; Unassembled WGS sequence.
DR GO; GO:0110001; C:toxin-antitoxin complex; IEA:InterPro.
DR GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR CDD; cd05403; NT_KNTase_like; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.20.120.580; bsu32300-like; 1.
DR InterPro; IPR008201; HepT-like.
DR InterPro; IPR037038; HepT-like_sf.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR041633; Polbeta.
DR PANTHER; PTHR33397:SF5; RNASE YUTE-RELATED; 1.
DR PANTHER; PTHR33397; UPF0331 PROTEIN YUTE; 1.
DR Pfam; PF01934; HepT-like; 1.
DR Pfam; PF18765; Polbeta; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000019140};
KW Toxin-antitoxin system {ECO:0000256|ARBA:ARBA00022649}.
FT DOMAIN 13..98
FT /note="Polymerase beta nucleotidyltransferase"
FT /evidence="ECO:0000259|Pfam:PF18765"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETX03475.1"
SQ SEQUENCE 286 AA; 32534 MW; 570FF384C0931528 CRC64;
VQRLSIIGAE LHARFPELLA LFLFGSTARG NANTTSDIDL AIFTDPRKEI TACSPLSSYA
VITSLLRTDR VDLLWLNQAP LLLQWEVVRT GILLFTSDAI AVAEFVEKVA REARDASTYA
RLCQTWYRTF LTQTYRDKRK GPMIDVRRIL EKIDYIRNTA KPVLAQLAEL DTGPFVNDPI
VLGAAKYYLQ SAVEAMLDMA NHIMARRGFG TFETHAKTFD ILTDHGLLRR EYLDTYKQMI
GLRNRLVHVY DDIDPAILHR ILVQDLDDFD RFIEDVTALL EQEPGG
//
