ID W4M456_9BACT Unreviewed; 313 AA.
AC W4M456;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Pyruvate synthase {ECO:0000313|EMBL:ETX04731.1};
GN ORFNames=ETSY2_27150 {ECO:0000313|EMBL:ETX04731.1};
OS Candidatus Entotheonella gemina.
OC Bacteria; Nitrospinae/Tectomicrobia group; Candidatus Tectomicrobia;
OC Entotheonella.
OX NCBI_TaxID=1429439 {ECO:0000313|EMBL:ETX04731.1, ECO:0000313|Proteomes:UP000019140};
RN [1] {ECO:0000313|EMBL:ETX04731.1, ECO:0000313|Proteomes:UP000019140}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TSY2 {ECO:0000313|Proteomes:UP000019140};
RX PubMed=24476823; DOI=10.1038/nature12959;
RA Wilson M.C., Mori T., Ruckert C., Uria A.R., Helf M.J., Takada K.,
RA Gernert C., Steffens U.A., Heycke N., Schmitt S., Rinke C., Helfrich E.J.,
RA Brachmann A.O., Gurgui C., Wakimoto T., Kracht M., Crusemann M.,
RA Hentschel U., Abe I., Matsunaga S., Kalinowski J., Takeyama H., Piel J.;
RT "An environmental bacterial taxon with a large and distinct metabolic
RT repertoire.";
RL Nature 506:58-62(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETX04731.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AZHX01001141; ETX04731.1; -; Genomic_DNA.
DR AlphaFoldDB; W4M456; -.
DR HOGENOM; CLU_058423_0_0_7; -.
DR Proteomes; UP000019140; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR PANTHER; PTHR42897; PYRUVATE SYNTHASE SUBUNIT PORB; 1.
DR PANTHER; PTHR42897:SF2; PYRUVATE SYNTHASE SUBUNIT PORB; 1.
DR Pfam; PF02775; TPP_enzyme_C; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Pyruvate {ECO:0000313|EMBL:ETX04731.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000019140}.
FT DOMAIN 57..223
FT /note="Thiamine pyrophosphate enzyme TPP-binding"
FT /evidence="ECO:0000259|Pfam:PF02775"
SQ SEQUENCE 313 AA; 34557 MW; 4AD9285E62970C97 CRC64;
MSIPMSSELE AIKNLKQISR EEFLLPGTSV CGGCGGLEAL RLAAKVLGPK TVFVNAAGCF
TLLAVFPYTP LKGSWLYTTM ASAAAGAQGV RDALDVLMER GKMKAEDDVD VVVVAGDGST
YDMAFSSISG AIFRQLDFWY FCYDNESYGN TGMQMSSATP YGARTATTPV SARTQEGTEH
GKKDLFEIWR AHHPAYLATV SPRYPVDLTN KFLKAKSLRG PKLFIAHAPC PTGWLYGPEH
TAEYARLAVD TGLFALKETV DGTVTHTHVP RRRRPVADYL QGQGRYRHLF EPERNETAIR
QIQAQVDRYW ETV
//
