ID W4VR60_9DIPT Unreviewed; 1509 AA.
AC W4VR60;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Pdz domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
OS Corethrella appendiculata.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Chaoboridae;
OC Corethrella.
OX NCBI_TaxID=1370023 {ECO:0000313|EMBL:JAB55511.1};
RN [1] {ECO:0000313|EMBL:JAB55511.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Salivary glands {ECO:0000313|EMBL:JAB55511.1};
RA Ribeiro J.M.C., Chagas A.C., Pham V.M., Lounibos L.P., Calvo E.;
RT "An insight into the sialome of the frog biting fly, Corethrella
RT appendiculata.";
RL Insect Biochem. Mol. Biol. 44:23-32(2014).
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DR EMBL; GANO01004360; JAB55511.1; -; mRNA.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR041489; PDZ_6.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR24135:SF28; LD13733P; 1.
DR PANTHER; PTHR24135; SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF17820; PDZ_6; 1.
DR Pfam; PF07653; SH3_2; 1.
DR SMART; SM00248; ANK; 6.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 3.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50002; SH3; 1.
PE 2: Evidence at transcript level;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT REPEAT 138..170
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 205..237
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 238..270
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 398..459
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 556..649
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 331..367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 656..790
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 817..841
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 897..921
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 930..949
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 964..993
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1024..1100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1112..1174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1187..1223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1304..1337
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1433..1488
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 656..691
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 746..790
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 817..839
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 897..913
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 934..948
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1024..1078
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1305..1335
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1447..1472
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1473..1488
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:JAB55511.1"
SQ SEQUENCE 1509 AA; 165131 MW; C099102B0054F8AA CRC64;
LPKELKESFN YGLFCPPSNG KAGKFLDEER RLGDYPFNGP VGYLELKYKR RVYKMLNLDE
RQLKALHTRA NLRRFLECIN GGHVEKIAKM CAKGLDPNFH CQETGETPLT IATGTKKPNK
LLIALVNGGA LLDYRTRDGV TALHRAVERD SLEAVSTLLE LGASPNYRDT KGLTPVYLCV
TKKTDSKICE VLLHDHATLG IQDTQGWHEV HQACRNGLVH HLEHLLFYGA DMDSQNASGN
TPLHVCAVNN QEACARMLLF RGAQRGSLNF ANQTPYQVAV IAGNLELAEM IQNYKCEDIV
PFRILDHFSL DINHDDALRL GWGATLSRAC GGPPSPCPSE HPFSSASSSL SEGSSSHRSH
EDDISIVTDK SLGDTSDIIS DSSGVGTNSD SAACSIGHPS TTVVCMETYN SNLSGHIQIQ
PGDVIEVVGS TDCGLLEGFV RGTNKTGFFP SQCVQEVQFR QKSIVTVSTS TPHHPYTTTN
NNNNNNNNIK INKNNINNSN KSTNSINNNN NEIDAEDDDN TTIHNELLSE QTDGYHQYNS
QTAPRMKKAT LSEPRNVVLH RAKRGFGFIL RGAKASSPLM QLKPSSRCPA LQYLDDVDPG
GVADMAGLKP GDFLLAINGE DVTCASHEHV VDLIRKSGSL VSMTVITLPT NLLQPNINNS
NSVNGSQDLQ QGQYPGSGMG TPLSSRQCAT LPRRMNGAGP MNKMPAPMPP RRDPKTTLSV
GRARAKSMVA GLEGGGEKCD DDDLSNPTTK STSAESIHQQ SQSAISTPTQ GGPGTPVQPR
TASIKARPTS SRITAAELEE LFQRQQGADG NRCSTMMSSS RFQSGFDSGA TTPPTSPQKG
PLVYASVADM KRKKSKNSTV RGRPCAIPQV GSDLKRTFHS TPDLHAFGVA NSLNSINSQS
SSSNSNWYNT VGHKGHRSQD DMHSLHMSMQ RLNLPPPNHP PPPPPVGQVV KVDVSRGEYE
SLTTLQKQMQ QKAKQQQQQQ QATTAKSQIQ DSDIMSSFKP EANAKLYASP QDIRNLSYKT
NELRKSSIKS NGGSPNTGPN NNGSGLSNNS NPYAQPGRPG NFAQQPQQQQ QYNQATPIIN
APPIPDPDYS LSESDGEEDN SVRLVRNVVN TINSNNNNNN NNNNNNNNNN IGGNGNTKKT
NDAQDSINPG MAAETSGNSN TSGSSSGSGS IPHSFSVDEI QKIKTKLKSS KSYPNDFLRN
QNLHPNQINE EGDNSSSGVS SDQEITITTN NTELIKSVQE QQKPPPEIIS VANETKSIKT
ATSTVTSTSP NNNTITTMAP VATKKVAPLN LEPKKVIQNA CPVVQSDDDD DQSPSPPSKG
FQRHNSLTRK QAASIAASRA KTMHATRHAV TLAHLPPPLE NDLDDVDSAY LMQRNVVTAN
NIPENLVFAP PPEFCDSIVE QHHQQQQQLQ QQQHYQQQQQ QQYHLHHQQQ QLQLQQQLYH
QQQLQHQHPH QHQHQHHQHQ HQHQHQHHHH QQQPQQKSAT TNCCNHASNT TTNKRVRIVG
AVPKMNNYK
//
