ID W5A3G2_WHEAT Unreviewed; 801 AA.
AC W5A3G2;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Hyperosmolality-gated Ca2+ permeable channel {ECO:0000313|EMBL:AKG97233.1, ECO:0000313|EMBL:AKH04341.1, ECO:0000313|EnsemblPlants:TraesCS1B02G211400.1};
GN Name=OSCA1.4 {ECO:0000313|EMBL:AKG97233.1};
GN Synonyms=TaOSCA1.4 {ECO:0000313|EMBL:AKH04341.1};
GN ORFNames=CFC21_006824 {ECO:0000313|EMBL:KAF6989492.1},
GN TRAES_3BF280400010CFD_c1 {ECO:0000313|EMBL:CDM81261.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EMBL:AKG97233.1};
RN [1] {ECO:0000313|EMBL:CDM81261.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25035497; DOI=10.1126/science.1249721;
RA Choulet F., Alberti A., Theil S., Glover N., Barbe V., Daron J.,
RA Pingault L., Sourdille P., Couloux A., Paux E., Leroy P., Mangenot S.,
RA Guilhot N., Le Gouis J., Balfourier F., Alaux M., Jamilloux V., Poulain J.,
RA Durand C., Bellec A., Gaspin C., Safar J., Dolezel J., Rogers J.,
RA Vandepoele K., Aury J.M., Mayer K., Berges H., Quesneville H., Wincker P.,
RA Feuillet C.;
RT "Structural and functional partitioning of bread wheat chromosome 3B.";
RL Science 345:1249721-1249721(2014).
RN [2] {ECO:0000313|EMBL:AKH04341.1}
RP NUCLEOTIDE SEQUENCE.
RA Li S., Guo Y., Lv G.;
RT "The gene cloning related production.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AKG97233.1}
RP NUCLEOTIDE SEQUENCE.
RA Li S., Guo Y., Lv G.;
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:KAF6989492.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF6989492.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [5] {ECO:0000313|EnsemblPlants:TraesCS1B02G211400.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS1B02G211400.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [6] {ECO:0000313|EnsemblPlants:TraesCS1B02G211400.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [7] {ECO:0000313|EMBL:KAF6989492.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF6989492.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
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DR EMBL; KR349666; AKG97233.1; -; mRNA.
DR EMBL; KR264897; AKH04341.1; -; Genomic_DNA.
DR EMBL; HG670306; CDM81261.1; -; Genomic_DNA.
DR EMBL; CM022212; KAF6989492.1; -; Genomic_DNA.
DR SMR; W5A3G2; -.
DR STRING; 4565.W5A3G2; -.
DR PaxDb; 4565-Traes_1BL_7F9006C51-1; -.
DR EnsemblPlants; TraesCS1B02G211400.1; TraesCS1B02G211400.1; TraesCS1B02G211400.
DR Gramene; TraesCS1B02G211400.1; TraesCS1B02G211400.1; TraesCS1B02G211400.
DR Gramene; TraesCS1B03G0617800.1; TraesCS1B03G0617800.1.CDS; TraesCS1B03G0617800.
DR eggNOG; KOG1134; Eukaryota.
DR HOGENOM; CLU_002458_7_1_1; -.
DR OMA; HEPMEWI; -.
DR OrthoDB; 1753647at2759; -.
DR Proteomes; UP000019116; Chromosome 1B.
DR Proteomes; UP000815260; Chromosome 1B.
DR ExpressionAtlas; W5A3G2; baseline.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IBA:GO_Central.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR PANTHER; PTHR13018:SF98; TO DEHYDRATION PROTEIN, PUTATIVE, EXPRESSED-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 2: Evidence at transcript level;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023303};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..128
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..390
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 423..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 463..482
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 570..600
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 622..641
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..175
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 196..358
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 369..641
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT REGION 732..801
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 732..763
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 801 AA; 93059 MW; 1B38B9DFD0CE2F37 CRC64;
MATLQDLGVS AFINILGAFV FLLLFAVLRI QPINDRVYFP KLYIAGKRAA DHRGARRAIN
LNLCTYFKFL SWVPGALRMT QTELIHHAGL DSAVYLRIYT LGLKIFLPVM VVALLVLIPV
NVSGGTLLNL RKDVMFSDID KLSISNVSPG SNRFFIHLLM AYVFTFWTCF MLYKEYSNVA
FMRLHFLASQ KRCADQFTVI VRNIPRVSSH STSEAVDEFF RRNHPDHYLG QQAVYNANRY
AKLVKQKERL QNWLDYYQLK FERHPEKRPT GRTGCFGFCG RQVDQIDYYR ARISELDKRI
ASERHRVLND PKAVMPVSFV TFDSRWGAAV CAQTQQSKNP TQWLTNWAPE PRDVYWQNLA
IPFFSLSIRK FLISIAVFAL VFFYMIPIAF VQSLANLEGI ERVAPFLRPV IEVKVVKSFL
QGFLPGLALK LFLYILPTVL MIMSKVEGYV SLSSLERRTA SKYYYFMLVN VFLGSIIAGT
AFEQLDSFFH DPPSQIPRTI GVAVPMKATF FMTYIMVDGW AGIANEILRV KPLVIYHLKN
MFIVKTERDR ERAMDPRSIA LGENLPSLQL YFLLGLVYAV VTPILLPFII VFFAFAYLVY
RHQIINVYNQ EYESAAAFWP QVHSRIIASL LISHVTLFGL LSTMKAAYST PLLIFLPLLT
LWFHKYCKSR FEPAFRKYPL EEAMEKDVME HASEPSLNLK TYLANAYLHP IFHMFEQEDQ
KEEATIEVRI DKSEQQQQHV RSSHSQYEEE TSAQTHYHHE ERSSSQYQYQ YQHQYQYQHE
ETHMRSEQSP PHFVYHHGVE H
//
