ID W5JAU9_ANODA Unreviewed; 2173 AA.
AC W5JAU9;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=BEACH domain-containing protein {ECO:0000259|PROSITE:PS50197};
GN ORFNames=AND_006727 {ECO:0000313|EMBL:ETN61582.1};
OS Anopheles darlingi (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=43151 {ECO:0000313|EMBL:ETN61582.1};
RN [1] {ECO:0000313|EMBL:ETN61582.1, ECO:0000313|Proteomes:UP000000673}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=20920257; DOI=10.1186/1471-2164-11-529;
RA Mendes N.D., Freitas A.T., Vasconcelos A.T., Sagot M.F.;
RT "Combination of measures distinguishes pre-miRNAs from other stem-loops in
RT the genome of the newly sequenced Anopheles darlingi.";
RL BMC Genomics 11:529-529(2010).
RN [2] {ECO:0000313|EMBL:ETN61582.1}
RP NUCLEOTIDE SEQUENCE.
RA Almeida L.G., Nicolas M.F., Souza R.C., Vasconcelos A.T.R.;
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ETN61582.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23761445;
RA Marinotti O., Cerqueira G.C., de Almeida L.G., Ferro M.I., Loreto E.L.,
RA Zaha A., Teixeira S.M., Wespiser A.R., Almeida E Silva A.,
RA Schlindwein A.D., Pacheco A.C., Silva A.L., Graveley B.R., Walenz B.P.,
RA Lima Bde A., Ribeiro C.A., Nunes-Silva C.G., de Carvalho C.R., Soares C.M.,
RA de Menezes C.B., Matiolli C., Caffrey D., Araujo D.A., de Oliveira D.M.,
RA Golenbock D., Grisard E.C., Fantinatti-Garboggini F., de Carvalho F.M.,
RA Barcellos F.G., Prosdocimi F., May G., Azevedo Junior G.M., Guimaraes G.M.,
RA Goldman G.H., Padilha I.Q., Batista Jda S., Ferro J.A., Ribeiro J.M.,
RA Fietto J.L., Dabbas K.M., Cerdeira L., Agnez-Lima L.F., Brocchi M.,
RA de Carvalho M.O., Teixeira Mde M., Diniz Maia Mde M., Goldman M.H.,
RA Cruz Schneider M.P., Felipe M.S., Hungria M., Nicolas M.F., Pereira M.,
RA Montes M.A., Cantao M.E., Vincentz M., Rafael M.S., Silverman N.,
RA Stoco P.H., Souza R.C., Vicentini R., Gazzinelli R.T., Neves Rde O.,
RA Silva R., Astolfi-Filho S., Maciel T.E., Urmenyi T.P., Tadei W.P.,
RA Camargo E.P., de Vasconcelos A.T.;
RT "The genome of Anopheles darlingi, the main neotropical malaria vector.";
RL Nucleic Acids Res. 41:7387-7400(2013).
RN [4] {ECO:0000313|EnsemblMetazoa:ADAC006727-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; ADMH02001646; ETN61582.1; -; Genomic_DNA.
DR STRING; 43151.W5JAU9; -.
DR EnsemblMetazoa; ADAC006727-RA; ADAC006727-PA; ADAC006727.
DR VEuPathDB; VectorBase:ADAC006727; -.
DR VEuPathDB; VectorBase:ADAR2_005092; -.
DR eggNOG; KOG1786; Eukaryota.
DR eggNOG; KOG4190; Eukaryota.
DR HOGENOM; CLU_001454_0_0_1; -.
DR OMA; AYEQFTP; -.
DR OrthoDB; 5491602at2759; -.
DR Proteomes; UP000000673; Unassembled WGS sequence.
DR CDD; cd06071; Beach; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR46866; GH12955P; 1.
DR PANTHER; PTHR46866:SF1; GH12955P; 1.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF00400; WD40; 1.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000673};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 390..669
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REPEAT 1877..1912
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 159..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 697..717
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1092..1112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1246..1277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1388..1421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1758..1792
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..177
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1393..1407
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1758..1782
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2173 AA; 240730 MW; 623061BD51BA5956 CRC64;
MMEAFMHEFS IPKHQIRETW HPNRWVLLVH KSWLRGLTHG GRVPKEFPTY GLADALEWPP
ENETGPWSRV YAAVYPKQST KVIPLPRSKH LTGATANDPL TSYGTDGGTV EDPLHYSQLL
QYVSSTNHKN AWKAAYRKYA GSRPDVTAIP PVANAVSSAF SEQQHPHHHQ SLSTKKGPGT
AAEPVSNPHI SVNAVTLPYD SVFREVLHRT FGCPILQQYS LNAPKDPDTG ITNQNASCAP
TVEGGSNASP AAAAANLFPA IATIETGTAF YIIYELYLTN NLLDCVTYSP AIIERSYNKP
LFIVYQLLQM MRSCHDRGLN VGDISLKDIY LTENLWIRVM PKLEANLLEY DEELLRQLGE
LQLIQERTAV GQQQQQQQQQ QSFLTPKPSA GLDLRYTLRE YCEMWCHGQL SNFDYLTILN
HMTGRRIGCP EFHHIMPWVT DFSSRSGQAW RDLKRSKFRL NKGDAQLDLT FQAATVGIAA
VHTDQQDAPV TVPHHVSDVL SEITYYVYMA RRTPKATLCK HVRPIWVPAE YPATIARLYE
WTPDECIPEF FSDPSVFKSI HEDLPDLEIP SWSSCPEDFV VKHRELLESQ YVSERLHHWI
DLTFGYKLTG GASIRSKNVC LSLVDKHQNL CHRGVVQLFA CPHPPRQFVT AWNSKTPPRW
HLQQDSNRRL TRSTEDLTRT IAGSNTGVLA PSAVEFRSHG DGSPRREEPG SAYRHSTQNL
PSQYHALKSE SSYHINVQPN SPGTLSLPKG YNPIAQLIAV ESLGTFRMKV FHATESCTPA
GGKQPDEYDL WCSRMDARPS AIGTGGNAFV NRIFSEAYER SFKGRSGEEV RSSGMGFSGD
PLQAQLQRQS LKQVLLHQRT KDLQVLGCLI VEIFLAPKLL PLGSCLRQEF DERFEAAKRL
VIDEPKALPL CLLPIVRQLL GLGDSSAIVT DRGLPPATPH QYLQPLLANL LIPFPSTYGR
LYRTIRALGA YDECVQLLEL QTFFECDGKN CSRYASLDRT RIEYRRRIAE CKVNACVALA
DPLLAPGGEQ FSVVELILPH IIELIRQDDT SIPAAWNMFD SLATALGVRK TQEYLLQPIL
ALYDSDEGDG FGGPGARPGA TTKPIGGDGS GTDPTTMLGM PGFIPAGGGG SSVKFTPRYT
SFKSEKSVKL YHHSFLLKLI VRFGLRCFLD HFIVPLVEAV GGYRDGDFQP CYHVHEPSVW
SGEFRKSRSY RSFKLNAATT VDPVSEHSNV DTTTLVSPNC SDKTISPTVA GRSFPLDDDP
ASVQETGSSS GVGVGGADEM FSFDEDSTLK RRSTIEDDEV AVEQAMRRII DDEPELGTSY
DLKLNLSQAE EALEESTLTE SAVASGSQEL KSPTIPIPSS FRRSIEFNSI GCEIGSKKSL
DSAEFLSKTP SEVTAKEPKE SGRTTHTSEL NRSRSVDSNR TIRSNRISEM SSESIVWLSH
RLGPVLTARY LSRNLLKMLT LCYIGAENLF PGETTGDERN QSPSPLTGGV EGLNHFSITD
GGVVGDGAAL RVIDCLTSIS ALFGEHFILA QYLPHAGEVI ALCRKKITVT LEGGLISALQ
LLKCLVPYLN DSTVMEQLSE VFLRQILHPA VRLLESTKYT MPNGFLARSV LARKLIDTLY
VLSVRIGREM TREHICVPAL QRFFLIFDKA YAHPDSLGAT TTVDPHSGMT SQGELPFGSF
TPPGVLLGEH APPNTAGADS SGGRMKAMEE IRDVFTPNLA YYSFIPFLNY LGQQEMARCV
RNLPLILNLC HEHEQMDYRR SSKGTGHSFD AQRSDEEEQS LQHQQQLDSL NCSNSFGSNI
IGNRIESGRD TDGSAVPMSS WTQLEHKDLL GLVTYKLDNV NSSRNLRGNW LAYWEHEIGR
SEKDTRLNLK QIKLQSYTGH SSSIKALLAL DNENSFISAS KDKTVKLWSL RSEGDGSKVS
SCQFTYANHR KSVHSLAFLE ALRLTISCDS GVHLWDPFVG SQIGQLDMPR HAPVSVVKTF
PSPNCLVLAG TPDSSVKLID ARTFSYCHEW KVALAPLGTV RTIAVAPSAN WIAVGLNSGH
IGVLDARTGG IIATWRANDN DLLQLLAPND AQLVSSSLDQ LIGVWNPSSG HLQYHMRTRP
EPVHCMANSG PELIVGTPTN RIGVYASILP DAPYSYTKLR SETFRGVLTS FALLPLNRMM
LVGGDNGTVT LLC
//
