ID W5JHS3_ANODA Unreviewed; 899 AA.
AC W5JHS3;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=IQ and AAA domain-containing protein {ECO:0000313|EMBL:ETN63666.1};
GN ORFNames=AND_004606 {ECO:0000313|EMBL:ETN63666.1};
OS Anopheles darlingi (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=43151 {ECO:0000313|EMBL:ETN63666.1};
RN [1] {ECO:0000313|EMBL:ETN63666.1, ECO:0000313|Proteomes:UP000000673}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=20920257; DOI=10.1186/1471-2164-11-529;
RA Mendes N.D., Freitas A.T., Vasconcelos A.T., Sagot M.F.;
RT "Combination of measures distinguishes pre-miRNAs from other stem-loops in
RT the genome of the newly sequenced Anopheles darlingi.";
RL BMC Genomics 11:529-529(2010).
RN [2] {ECO:0000313|EMBL:ETN63666.1}
RP NUCLEOTIDE SEQUENCE.
RA Almeida L.G., Nicolas M.F., Souza R.C., Vasconcelos A.T.R.;
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ETN63666.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23761445;
RA Marinotti O., Cerqueira G.C., de Almeida L.G., Ferro M.I., Loreto E.L.,
RA Zaha A., Teixeira S.M., Wespiser A.R., Almeida E Silva A.,
RA Schlindwein A.D., Pacheco A.C., Silva A.L., Graveley B.R., Walenz B.P.,
RA Lima Bde A., Ribeiro C.A., Nunes-Silva C.G., de Carvalho C.R., Soares C.M.,
RA de Menezes C.B., Matiolli C., Caffrey D., Araujo D.A., de Oliveira D.M.,
RA Golenbock D., Grisard E.C., Fantinatti-Garboggini F., de Carvalho F.M.,
RA Barcellos F.G., Prosdocimi F., May G., Azevedo Junior G.M., Guimaraes G.M.,
RA Goldman G.H., Padilha I.Q., Batista Jda S., Ferro J.A., Ribeiro J.M.,
RA Fietto J.L., Dabbas K.M., Cerdeira L., Agnez-Lima L.F., Brocchi M.,
RA de Carvalho M.O., Teixeira Mde M., Diniz Maia Mde M., Goldman M.H.,
RA Cruz Schneider M.P., Felipe M.S., Hungria M., Nicolas M.F., Pereira M.,
RA Montes M.A., Cantao M.E., Vincentz M., Rafael M.S., Silverman N.,
RA Stoco P.H., Souza R.C., Vicentini R., Gazzinelli R.T., Neves Rde O.,
RA Silva R., Astolfi-Filho S., Maciel T.E., Urmenyi T.P., Tadei W.P.,
RA Camargo E.P., de Vasconcelos A.T.;
RT "The genome of Anopheles darlingi, the main neotropical malaria vector.";
RL Nucleic Acids Res. 41:7387-7400(2013).
RN [4] {ECO:0000313|EnsemblMetazoa:ADAC004606-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; ADMH02001207; ETN63666.1; -; Genomic_DNA.
DR AlphaFoldDB; W5JHS3; -.
DR STRING; 43151.W5JHS3; -.
DR EnsemblMetazoa; ADAC004606-RA; ADAC004606-PA; ADAC004606.
DR VEuPathDB; VectorBase:ADAC004606; -.
DR VEuPathDB; VectorBase:ADAR2_000852; -.
DR eggNOG; KOG0740; Eukaryota.
DR eggNOG; KOG4439; Eukaryota.
DR HOGENOM; CLU_005923_0_0_1; -.
DR OMA; EEGWKMA; -.
DR OrthoDB; 200191at2759; -.
DR Proteomes; UP000000673; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR PANTHER; PTHR14690:SF0; IQ AND AAA DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR14690; UNCHARACTERIZED; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00612; IQ; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50096; IQ; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000673}.
FT DOMAIN 728..894
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 312..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 452..479
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 327..346
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 348..363
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 454..471
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 899 AA; 103408 MW; 8C11AC37564322A2 CRC64;
MSNRTFNLLW TGAQKDLEKL AVNDFEYQAI EAQHDRGEIQ GQVFELYLRY LVISNRLEEI
YDQIVQPQKR ILIRKLLDNC LGRVLELKHD LVVIDMTEFS YNDTVVEKLS LTPLSMEINV
PRYFRREREE QLNERKKFMD DILKKIGALD EEVVEEELSE LEAIRIIQTH ERARQGRLRA
QFMKELKILK EKGKPDSSRD KSTTGLNAAM KIQKTWRGYA TRRQTRRKKM EEMILIGMVP
PPVTSARTAI DELEDLKQFR YKQQKQFQDD YERSLVRVKE EISVKQGAAM TEDIADEIRT
WFKEYQKRTG RLPDFPSEEA GGSRHLLSRQ GTESEMSRSS VMSSRESKLK GGGKEKLAQK
KPGELSLEEG LDKAFKPMQS SFLPEIKCGI EEYTDVWKGK DESQNLRQTY YDDMIYEEKY
ADVEAELRRI VDEIMRQELE LLQIALERDR GGKKLKKSSK KARRSGKKGK KKKDKDLTPD
RTTESLFEEL VTNGIIKKYP ETPIKSYVGD LSYAARSALN PSPGDVRQLI KQYCILPLGS
ETIRNFGPCI KSLLIAGPKG SGKTSLVHAI CTETGSVLFD ISPPNIVGKY PGKSGLIMLM
HLISKVSRLL QPSVIYFGDA EKPFMKKIPK TDRTDPKRLK KDLPKLVKNI QPEDRIMLIG
TSDCPWEADM KLMVQTYQRF IYIPRPDYGA LSFAWKELLS HYSGVHRQFD TGAMAKISDG
YTIGSVVRCI REVITCKRML QLRVHPLTHL ELINALSALE PVYKEEEEAF LYWWCKTPLG
RRRSKQLEKD HEAMMEMENI MLLSLTAGGV GLNLVGANHL FLLDPHWNPQ LEAQAQDRIY
RVGQTKPVHI WKFICQETVE QKILALQQHK LEIADGVLTG TGNKGSKLTI DDLKSLFGL
//
