ID W5JR05_ANODA Unreviewed; 777 AA.
AC W5JR05;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Mitotic checkpoint protein mad1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=AND_002479 {ECO:0000313|EMBL:ETN65738.1};
OS Anopheles darlingi (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=43151 {ECO:0000313|EMBL:ETN65738.1};
RN [1] {ECO:0000313|EMBL:ETN65738.1, ECO:0000313|Proteomes:UP000000673}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=20920257; DOI=10.1186/1471-2164-11-529;
RA Mendes N.D., Freitas A.T., Vasconcelos A.T., Sagot M.F.;
RT "Combination of measures distinguishes pre-miRNAs from other stem-loops in
RT the genome of the newly sequenced Anopheles darlingi.";
RL BMC Genomics 11:529-529(2010).
RN [2] {ECO:0000313|EMBL:ETN65738.1}
RP NUCLEOTIDE SEQUENCE.
RA Almeida L.G., Nicolas M.F., Souza R.C., Vasconcelos A.T.R.;
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ETN65738.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23761445;
RA Marinotti O., Cerqueira G.C., de Almeida L.G., Ferro M.I., Loreto E.L.,
RA Zaha A., Teixeira S.M., Wespiser A.R., Almeida E Silva A.,
RA Schlindwein A.D., Pacheco A.C., Silva A.L., Graveley B.R., Walenz B.P.,
RA Lima Bde A., Ribeiro C.A., Nunes-Silva C.G., de Carvalho C.R., Soares C.M.,
RA de Menezes C.B., Matiolli C., Caffrey D., Araujo D.A., de Oliveira D.M.,
RA Golenbock D., Grisard E.C., Fantinatti-Garboggini F., de Carvalho F.M.,
RA Barcellos F.G., Prosdocimi F., May G., Azevedo Junior G.M., Guimaraes G.M.,
RA Goldman G.H., Padilha I.Q., Batista Jda S., Ferro J.A., Ribeiro J.M.,
RA Fietto J.L., Dabbas K.M., Cerdeira L., Agnez-Lima L.F., Brocchi M.,
RA de Carvalho M.O., Teixeira Mde M., Diniz Maia Mde M., Goldman M.H.,
RA Cruz Schneider M.P., Felipe M.S., Hungria M., Nicolas M.F., Pereira M.,
RA Montes M.A., Cantao M.E., Vincentz M., Rafael M.S., Silverman N.,
RA Stoco P.H., Souza R.C., Vicentini R., Gazzinelli R.T., Neves Rde O.,
RA Silva R., Astolfi-Filho S., Maciel T.E., Urmenyi T.P., Tadei W.P.,
RA Camargo E.P., de Vasconcelos A.T.;
RT "The genome of Anopheles darlingi, the main neotropical malaria vector.";
RL Nucleic Acids Res. 41:7387-7400(2013).
RN [4] {ECO:0000313|EnsemblMetazoa:ADAC002479-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the MAD1 family.
CC {ECO:0000256|ARBA:ARBA00008029}.
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DR EMBL; ADMH02000584; ETN65738.1; -; Genomic_DNA.
DR AlphaFoldDB; W5JR05; -.
DR STRING; 43151.W5JR05; -.
DR EnsemblMetazoa; ADAC002479-RA; ADAC002479-PA; ADAC002479.
DR VEuPathDB; VectorBase:ADAC002479; -.
DR VEuPathDB; VectorBase:ADAR2_003348; -.
DR eggNOG; KOG4593; Eukaryota.
DR HOGENOM; CLU_393441_0_0_1; -.
DR OMA; RDFYKQM; -.
DR OrthoDB; 8224at2759; -.
DR Proteomes; UP000000673; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IEA:InterPro.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 3.30.457.60; -; 1.
DR Gene3D; 6.10.250.90; -; 1.
DR InterPro; IPR008672; Mad1.
DR PANTHER; PTHR23168:SF0; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1; 1.
DR PANTHER; PTHR23168; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1; 1.
DR Pfam; PF05557; MAD; 1.
DR SUPFAM; SSF75704; Mitotic arrest deficient-like 1, Mad1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000000673}.
FT COILED 153..201
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 231..385
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 431..472
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 500..682
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 777 AA; 89441 MW; 6B84F1A0E76D2F13 CRC64;
MGCSTARVLL PFQSSSAVLV HGFSKNELFS EFCAAECNKN VLSGAMMDIG RDEESADVTR
LSNSSFEISR KKRRISGLGL SGVHDTINDV NTSTESLSST VNSTQLVAQS PWETRRMKAD
LIEARSRITV LKKEIEHQNT VMATNQLRNQ HKISSLEQEL AHSSKKAAEL EKHLTAVRKR
EHAAKEELVR TRNQFNQLKQ SSDEQQFELQ SSLAKLEQKY NCDTSELGSE IRELTAQVSD
LMLQMSGVQE ELDVTRGIND TLQSKADAYD QTKRELEQTI SKLEETESRV KKLEFECGSH
GDWQKLSKAT TARLKKSTEY EHENIRMREE LKNLRDLIGN KLLLEEQVSN LQARVDRYEQ
QEAAAATIEV RVKELENELN DWKQLGRDYC PKKDGTQRSE PSAALLRHHI AQLLQKDVIL
TSEQSTAVSE QHQTREAFDR LRMEKDSLEK QSEEYKRSLK HYQLVLQRVQ RKLKLVISER
DCLKQVVENF ENDLTIDHSI AQAGQDSQQL QERIKSLEKV LTNYQEHCQK LEAEIQSKQV
VSDTEVSNAL TSEQYQELRK EIDSLRMENQ TIRRRKQELE LEIEQNRVRS IAPILRHTDS
LAVQAFDQHQ NSVEKLQAEI ERLRAKIRSM QENGGEQHLE ATVTNSNMTM NVMELNNMRA
KAEMLESKMK QMKEKFREAS VEFRDICYLL FGYRVDRVSN NNYRVRSMYA DNDEDYLNFQ
LDESSGKLNM LASRYGQSLL EQVDGLLNMH GSLPVFLSTL TLDLFKRTTI MDATSDG
//
