ID W5JY55_ASTMX Unreviewed; 370 AA.
AC W5JY55;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=RUN domain-containing protein 3A {ECO:0000313|Ensembl:ENSAMXP00000000265.2};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000000265.2, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000000265.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RUNDC3 family.
CC {ECO:0000256|ARBA:ARBA00034727}.
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DR AlphaFoldDB; W5JY55; -.
DR Ensembl; ENSAMXT00000000265.2; ENSAMXP00000000265.2; ENSAMXG00000032752.1.
DR eggNOG; KOG4381; Eukaryota.
DR GeneTree; ENSGT00940000158922; -.
DR HOGENOM; CLU_045987_0_0_1; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000032752; Expressed in brain and 11 other cell types or tissues.
DR Gene3D; 1.20.58.900; -; 1.
DR InterPro; IPR004012; Run_dom.
DR InterPro; IPR037213; Run_dom_sf.
DR InterPro; IPR047340; RUNDC3A_B.
DR PANTHER; PTHR46251; RUN DOMAIN-CONTAINING 3 PROTEIN RUNDC3; 1.
DR PANTHER; PTHR46251:SF5; RUN DOMAIN-CONTAINING PROTEIN 3A; 1.
DR Pfam; PF02759; RUN; 1.
DR SMART; SM00593; RUN; 1.
DR SUPFAM; SSF140741; RUN domain-like; 1.
DR PROSITE; PS50826; RUN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000018467}.
FT DOMAIN 1..161
FT /note="RUN"
FT /evidence="ECO:0000259|PROSITE:PS50826"
FT COILED 251..285
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 370 AA; 42627 MW; 42FBE024AA9D20CB CRC64;
MEAKRSTAVE RRNLLTVCKF GLKRNNLFMW FLLKKIECKR NTVNYYVSVC SLTGSGSWFD
GQRSFWDFIR LACSKLQNNC IGSIENMENI NSSRAKGRAW IRVALMEKRL SEYIATALRD
SRTTRRFYDE GAIMLREEAS VLTGMLIGLG AIDFSFCLKG EALDGKSEAV IDYTPYLKFT
QSYDYLSDDD DCRSVDSSNS DDSVPEHPYI PLVTDEESWS NKCRRMEQRF KIVNAQKGYL
EELVRLRESQ LKNVETENKR MSSRLEELQL QSHQEKRELE SIILELQEQL TSLIPVESHP
LSKDMSIPLV NQWPSLHTYN NQEDSKLYRR GSFPSPELLS AHISLDSDSQ KLEGKQNGQP
WCAAGKSFKL
//
