ID W5K959_ASTMX Unreviewed; 313 AA.
AC W5K959;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Uncharacterized LOC103028022 {ECO:0000313|Ensembl:ENSAMXP00000004120.2};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000004120.2, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000004120.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007244134.1; XM_007244072.2.
DR AlphaFoldDB; W5K959; -.
DR STRING; 7994.ENSAMXP00000004120; -.
DR Ensembl; ENSAMXT00000004120.2; ENSAMXP00000004120.2; ENSAMXG00000004032.2.
DR GeneID; 103028022; -.
DR KEGG; amex:103028022; -.
DR CTD; 100001799; -.
DR GeneTree; ENSGT00390000012630; -.
DR InParanoid; W5K959; -.
DR OrthoDB; 4262391at2759; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000004032; Expressed in mesonephros and 8 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR48397:SF2; INTERLEUKIN-12 SUBUNIT BETA; 1.
DR PANTHER; PTHR48397; INTERLEUKIN-12 SUBUNIT BETA-RELATED; 1.
DR Pfam; PF07679; I-set; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00408; IGc2; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
PE 4: Predicted;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Reference proteome {ECO:0000313|Proteomes:UP000018467};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..313
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017345374"
FT DOMAIN 29..105
FT /note="Immunoglobulin subtype"
FT /evidence="ECO:0000259|SMART:SM00409"
FT DOMAIN 35..95
FT /note="Immunoglobulin subtype 2"
FT /evidence="ECO:0000259|SMART:SM00408"
FT REGION 283..313
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 297..313
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 313 AA; 36185 MW; E7D51722C66FB4FC CRC64;
MSRMSSALSA ICIVFLGIMR VSAVDTFPKK FVAVQMNSDV TLHCDTTDQD VTWQYDSDEL
EASEDIRLEG NKLILKRIEE EQAGNYTCWR NNEIVDYTYV LLDMTSHITD LTINCTAETF
NCTFNISCNM NQPAFNYFRL RNKRDNSNWV MPSEDGAFHL THSTNPYAEE AKQLEVIGEA
VSSSDRYFKI SHNFYLRDII KPACPEVSVN KRKVNLAPPP TWAKPTSYYP LDHEIQCKNL
DDGKEKPCDL DHDNKVPKGT SELRVRCRDS LLLSQWSDWT PWHNVHKNRR NNRKEGKRMG
RKETAKNGKK RDS
//
