ID W5KHZ5_ASTMX Unreviewed; 518 AA.
AC W5KHZ5;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Heterogeneous nuclear ribonucleoprotein L like {ECO:0000313|Ensembl:ENSAMXP00000007207.2};
GN Name=HNRNPLL {ECO:0000313|Ensembl:ENSAMXP00000007207.2};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000007207.2, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000007207.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; W5KHZ5; -.
DR STRING; 7994.ENSAMXP00000007207; -.
DR Ensembl; ENSAMXT00000007207.2; ENSAMXP00000007207.2; ENSAMXG00000007014.2.
DR eggNOG; KOG1456; Eukaryota.
DR GeneTree; ENSGT01030000234642; -.
DR HOGENOM; CLU_015171_0_0_1; -.
DR InParanoid; W5KHZ5; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000007014; Expressed in brain and 14 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR Gene3D; 3.30.70.330; -; 4.
DR InterPro; IPR006536; HnRNP-L/PTB.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR021790; PTBP1-like_RRM2.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR NCBIfam; TIGR01649; hnRNP-L_PTB; 1.
DR PANTHER; PTHR15592:SF13; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN L-LIKE; 1.
DR PANTHER; PTHR15592; MATRIN 3/NUCLEAR PROTEIN 220-RELATED; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF13893; RRM_5; 1.
DR Pfam; PF11835; RRM_8; 1.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 4.
DR PROSITE; PS50102; RRM; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018467};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 60..134
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 311..385
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
SQ SEQUENCE 518 AA; 57786 MW; 9C5DB030D4F4D955 CRC64;
VLSEGFEGLM LSLSDREFLL QTKTPNTFHL LLPARERDVV LLSLCLQDNG DDTHRIAPSP
VVHVRGLCES VVEADLVESL EKFGNICYVM MMPFKRQALV EFEDVESADR CVACGSKEAV
YIAGQQAYFN YSTSKRITRP TNADDPNSGN KVLLLSIQNP LYPITTDVLY TVCNPIGNVL
RIVIFKRNGI QAMNAQKAKA ALNGADIYAG CCTLKIEYAR PSRLNVIRND NDSWDYTKPF
LVRRERGKGR QRQAILGEHP SSYSDNGYGS HCPLLPLPSN NRFKRSSHEV PDVVAYPLPQ
TSSYIGHSSS SVAMVSGLHS TKMNCTRIFN LFCLYGNIEK VKFMKSVPGT ALVEMGDEYA
VDRAITHLNS IKVFSKRLNV CVSKQHAVIP SQVFELEDGT SSYKDFAMTR NNRFTSAGQA
SKNIIQPPSC VLHFYNVPPC ITEDDLLRLC TEHDVPGFIK FKMFDAKPSS KTISGLLEFD
SKTHAVEVLT VLNHYQIRIP NGSNPYTLKL CFSTSSHL
//
