ID W5KJC9_ASTMX Unreviewed; 762 AA.
AC W5KJC9;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Chondroadherin-like protein {ECO:0000313|Ensembl:ENSAMXP00000007691.2};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000007691.2, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000007691.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; W5KJC9; -.
DR Ensembl; ENSAMXT00000007691.2; ENSAMXP00000007691.2; ENSAMXG00000007483.2.
DR eggNOG; KOG0619; Eukaryota.
DR GeneTree; ENSGT00940000165277; -.
DR HOGENOM; CLU_022061_0_0_1; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000007483; Expressed in camera-type eye and 7 other cell types or tissues.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR24373:SF373; CHONDROADHERIN-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR24373; SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN; 1.
DR Pfam; PF13855; LRR_8; 6.
DR Pfam; PF01463; LRRCT; 2.
DR SMART; SM00364; LRR_BAC; 5.
DR SMART; SM00369; LRR_TYP; 19.
DR SMART; SM00082; LRRCT; 2.
DR SMART; SM00013; LRRNT; 2.
DR SUPFAM; SSF52058; L domain-like; 2.
DR PROSITE; PS51450; LRR; 4.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000018467};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..762
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017318636"
FT DOMAIN 28..62
FT /note="LRRNT"
FT /evidence="ECO:0000259|SMART:SM00013"
FT DOMAIN 306..354
FT /note="LRRCT"
FT /evidence="ECO:0000259|SMART:SM00082"
FT DOMAIN 383..417
FT /note="LRRNT"
FT /evidence="ECO:0000259|SMART:SM00013"
FT DOMAIN 663..710
FT /note="LRRCT"
FT /evidence="ECO:0000259|SMART:SM00082"
SQ SEQUENCE 762 AA; 84892 MW; 1AA52BB805BFD5E4 CRC64;
MKGKMCSLGV WPIALLLLLC ICEAKAAKCT RFCICDSIQL TVACVNKNLT EVPPSIDEIT
VKLDLRGNNL QELPTGAFSH TPYLTHLSLQ RSKILKVREG AFRSLGRLVF LNLAYNDIEI
LYQESFDGLS SLKQLLIDHN RIEEIQPGAF SQLGFLNLLS ITHNRLEYIP NMAFQGLQNI
KWLRLSHNAL NYLDIEAFAG LFTLTRLSLD NNGVQFFPTE TMTRLPEVTR LDLSYNPMTY
LGEEVVSMAK LTHLFLDHNS LQDFSNSAVL LSPRLTHLDL SHNQLRVLQP LVPESPKLTR
LNLAGNPIYC SCYLRPLREW AIRERVRLGG ACRGPPHLSE ENLDAVQPAD LRCQSQEAML
KAELEEMNRF PAPPTTPPPD QIQCPANCVC EAENHHSSCE NKGHTKVPRG FSPNTRLLDL
RDNHFHYIPT NSFPGVPEVV SLHLQRCKIH EVENGAFSGM KGLVYLYLSE NDLTSLSPDA
FKGLPQLTYL HLEKNRFTQF PKGAFKLLPG LLALHLENNA IAKLDSGILM GAEKLRGLFL
TSNAITYINP RAFDPAPDLD TLHLGSNKLK EVPSTALSKT SSLAELRLSY NSIRWVGPEA
FSPVGASLRH LYLDNVGLEK MSKDAFTGLG SGLRSLFLEG NQLEDVPDLN PLTGLEAINL
AENPLLCDCP LLPLRRWIES VNLKVRATCA YPPELRGQKV KDVHVFKSCP GERPYPTRTP
YTSKAPKATK SKPALIGAPK VMKVAKVKPR VSVGRDGRSE GN
//
