ID W5LX94_LEPOC Unreviewed; 897 AA.
AC W5LX94;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=ATP-grasp domain-containing protein {ECO:0000259|PROSITE:PS50975};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000000751.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000000751.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; W5LX94; -.
DR STRING; 7918.ENSLOCP00000000751; -.
DR Ensembl; ENSLOCT00000000755.1; ENSLOCP00000000751.1; ENSLOCG00000000679.1.
DR eggNOG; ENOG502QRI6; Eukaryota.
DR GeneTree; ENSGT00960000189182; -.
DR HOGENOM; CLU_315906_0_0_1; -.
DR InParanoid; W5LX94; -.
DR OMA; PISCFPG; -.
DR Proteomes; UP000018468; Unassembled WGS sequence.
DR Bgee; ENSLOCG00000000679; Expressed in muscle tissue and 6 other cell types or tissues.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0047730; F:carnosine synthase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0035499; P:carnosine biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.20; -; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR031046; CARNS1.
DR PANTHER; PTHR48066; CARNOSINE SYNTHASE 1; 1.
DR PANTHER; PTHR48066:SF1; CARNOSINE SYNTHASE 1; 1.
DR Pfam; PF15632; ATPgrasp_Ter; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR PROSITE; PS50975; ATP_GRASP; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT DOMAIN 576..789
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
SQ SEQUENCE 897 AA; 97726 MW; 95F6C8D43D94425B CRC64;
MLFQLLQDAL RELGLPLTRD GTFLGGAPAA AMCICVLGSP LPYLSLLLEA GTVSPGDALL
CLSPTWLSCC PSPPSTLLLV HRAVSFDLGG RTQLLTFDPP RQVTYFLPCA PWAEQIQEVT
RELDCPMGGS ADLFQFWGDT LNARIALQRG GLCCPPTLAV VLSPLTDKLN YGGDEAGVCI
VEVTDFMKEE EEERVRKAVQ SFLESAVVQR SGKVVLKSSR AQWPGRAGIP VRFLDQKNLE
AVWAGLCSLL PLLEKGEAAL LEAYCPTLTR NHLCVSDANI PAPELSMKIC AIVTRSPQDV
PLLYKLVCRV GVSDSPLSHR DSLPQSLNTA LREWGFSDPS FCLSVHRLLS QTAQRCLRVV
MDTEAGLSPD QRGGIAAQTD LIGVDMLLCL SNGSAELTPV VLGLHSWQCL QSCALGTAAM
TGKEERGEAE SPGSLLHTPL TRSQRHLLRG KSVLVIGAGR ISKKFVWESA RDYGLKIFLV
ESDPSHFAAG LVSRFLAMDV TDHQQDEEHC ARICAWLSQN DLQPDGCLCF WDDCIVLASL
ICQHLGLRGP PPEAVQTSKE KSRTHLHLLG LSSSSQDLFP SPRIYAVPCA HVESAADIQK
VVTDGEIGDG SIKLRFPAIM KLEYGAGAVG VKRVDSLSES LAHLEKIAGD LREETDYPGI
GLGWGNAMTL MEYIGGTEHD VDVVIFDGRL EGAFVSDNGP TRVPGFTETA AQMPTGLPRD
KEAQLIEAAY RCCLGCGLRD GVFNVEMKMT PSGPKLIEIN ARMGGFYLRD WIREIFGVDI
LFCAFLIACG LAPRLPPQRL PALCHLTGVM CVVSQHLHAL RTTASPPVLR ELHRRGVLRL
CEMEEELIAG EYEEPYCNVG VRAERPQDAR LSLLTLSQAL GIDSPHYPVS YFLSHFK
//
