ID W5M5I2_LEPOC Unreviewed; 609 AA.
AC W5M5I2;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Lamin B2 {ECO:0000313|Ensembl:ENSLOCP00000003640.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000003640.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000003640.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AHAT01011189; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01011190; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5M5I2; -.
DR STRING; 7918.ENSLOCP00000003640; -.
DR Ensembl; ENSLOCT00000003647.1; ENSLOCP00000003640.1; ENSLOCG00000003086.1.
DR eggNOG; KOG0977; Eukaryota.
DR GeneTree; ENSGT00940000160274; -.
DR HOGENOM; CLU_012560_9_2_1; -.
DR InParanoid; W5M5I2; -.
DR OMA; EMTQMRD; -.
DR Proteomes; UP000018468; Linkage group LG19.
DR Bgee; ENSLOCG00000003086; Expressed in embryo and 13 other cell types or tissues.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005635; C:nuclear envelope; IBA:GO_Central.
DR GO; GO:0005652; C:nuclear lamina; IBA:GO_Central.
DR GO; GO:0005200; F:structural constituent of cytoskeleton; IBA:GO_Central.
DR GO; GO:0031507; P:heterochromatin formation; IBA:GO_Central.
DR GO; GO:0006998; P:nuclear envelope organization; IBA:GO_Central.
DR GO; GO:0007097; P:nuclear migration; IBA:GO_Central.
DR GO; GO:0051664; P:nuclear pore localization; IBA:GO_Central.
DR GO; GO:0090435; P:protein localization to nuclear envelope; IBA:GO_Central.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 2.60.40.1260; Lamin Tail domain; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR001322; Lamin_tail_dom.
DR InterPro; IPR036415; Lamin_tail_dom_sf.
DR PANTHER; PTHR45721; LAMIN DM0-RELATED; 1.
DR PANTHER; PTHR45721:SF2; LAMIN-B2; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF00932; LTD; 1.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR SUPFAM; SSF74853; Lamin A/C globular tail domain; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
DR PROSITE; PS51841; LTD; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754};
KW Methylation {ECO:0000256|ARBA:ARBA00022481};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT DOMAIN 52..408
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT DOMAIN 457..574
FT /note="LTD"
FT /evidence="ECO:0000259|PROSITE:PS51841"
FT REGION 25..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 405..424
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 429..452
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 581..609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 56..224
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 320..390
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 26..44
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 409..424
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 609 AA; 68980 MW; 62B54D5848D99300 CRC64;
KPRSPSTNSN VSRPIVCVCE MATATPSRSA AGTPRQSADT PLSPTRISRL QEKEELRHLN
DRLAVYIDRV RALELENDRL MVKVSEKEEV TTREVTGIKS LYEVELADAR RVLDETARDR
ARLQIDLGKA NAELEEVTRN YKKKDGDLAA AQARIKELEA QCNKSGADLN TALSENRALL
AEVNELKAQL AKAEDAHTVA KKQLEAETLM RVDLENRCQS LQEDLNFRKN IYDEEVQETR
RRHERRMVEV DSGRQQEYEY KLSAALQDLR RQHDEQVAIY KQELENTFQA KLENAKVSSD
MNDKAVSTAR EELQEAHMRI ESLGYQLTAL QKQASAAEER IRELEDLLAS DRDKYRRQLD
AKEREMAEMR DQMQQQLNEY QELLDVKLAL DMEISAYNKL LEGEESRLKL SPSPSSRVTV
SRVTSSSLAS ASVTRSSRAK RKRVEMEESG TVGQPRFQIS QQAETTGSIT IEEIDLEGKS
VTLKNNAEKD QSLGNWRLKR RIGDGDEIAY KFTPKYLLKA GQTVTVWSAD AGVTHAPPSN
LLWKTQSSWG TGDDIVTFLV NSDGEEVAKR TVTKSLVEVE EEEDADFGEE DLFHQQGDPK
AASRECLIM
//
