ID   W5MHQ4_LEPOC            Unreviewed;       576 AA.
AC   W5MHQ4;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Ceramide kinase like {ECO:0000313|Ensembl:ENSLOCP00000007913.1};
OS   Lepisosteus oculatus (Spotted gar).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC   Lepisosteus.
OX   NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000007913.1, ECO:0000313|Proteomes:UP000018468};
RN   [1] {ECO:0000313|Proteomes:UP000018468}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT   "The Draft Genome of Lepisosteus oculatus.";
RL   Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLOCP00000007913.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AHAT01020117; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; W5MHQ4; -.
DR   Ensembl; ENSLOCT00000007923.1; ENSLOCP00000007913.1; ENSLOCG00000006533.1.
DR   GeneTree; ENSGT00940000157578; -.
DR   HOGENOM; CLU_013399_2_0_1; -.
DR   Proteomes; UP000018468; Linkage group LG12.
DR   Bgee; ENSLOCG00000006533; Expressed in bone element and 12 other cell types or tissues.
DR   GO; GO:0016301; F:kinase activity; IEA:InterPro.
DR   Gene3D; 2.60.200.40; -; 1.
DR   InterPro; IPR017438; ATP-NAD_kinase_N.
DR   InterPro; IPR045363; CERK_C.
DR   InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR   InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR   PANTHER; PTHR12358:SF26; CERAMIDE KINASE-LIKE PROTEIN; 1.
DR   PANTHER; PTHR12358; SPHINGOSINE KINASE; 1.
DR   Pfam; PF19280; CERK_C; 1.
DR   Pfam; PF00781; DAGK_cat; 1.
DR   SMART; SM00046; DAGKc; 1.
DR   SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR   PROSITE; PS50146; DAGK; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT   DOMAIN          200..349
FT                   /note="DAGKc"
FT                   /evidence="ECO:0000259|PROSITE:PS50146"
FT   REGION          20..81
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        66..81
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   576 AA;  64547 MW;  C62E4C982EE4B70A CRC64;
     MFESPRRCGN ILNAWSESLE ELQETQPVSP VSTDNPGKKR KKKKREQQRS FSVPQLFTAA
     SVASDPEERN RGDTDQRAET EEPIVRGIFQ IEKRSCDVVL TATRVIWTQI QPETPTGDIK
     ASETNQDEYV ELKDIFAVKL KRRRSVGQQT GGTLLGITLF QCVRKGKKLK DHAIHLSNLS
     VDHCEVWFKH LKDLLNGFRN RPKSLKVFVN PNSHKKEAHQ IYKEQVEPLF KLADIKTDIT
     ITENKGQALS ILKECKLDEY DGVVCVGGDG TASEVAYGLL LRAQMDAGRD TDSIFTPVRA
     PLPLGIIPAG STDVVACSVH GIRHPVTAAM HIIMGHLQSV DVCTFSSHSR LLRFGFSAMF
     GFGGRTLALA EKHRWMPSNQ RREFAVIKTL ANLKPEDCEL SFLPLTQSQK VTEGKNDEEE
     WQKIKGLFLN ISIMAIPCLC SMAPRGLAPN TRLDNGSMAL IVVRNTSRAD FIKHLKRYGS
     LKNQFSFSFV ETYTVQAVKV RPRPWSGWGD DTLEENVEID SKNTPMISSE GSYPWNIDGD
     LMEASEVCIR VHPQLITLFG VNTEEVDEST VKCSCI
//