ID W5MND7_LEPOC Unreviewed; 338 AA.
AC W5MND7;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=G protein-coupled receptor 26 {ECO:0000313|Ensembl:ENSLOCP00000009896.1};
GN Name=GPR26 {ECO:0000313|Ensembl:ENSLOCP00000009896.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000009896.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000009896.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AHAT01004030; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006630587.1; XM_006630524.2.
DR AlphaFoldDB; W5MND7; -.
DR STRING; 7918.ENSLOCP00000009896; -.
DR Ensembl; ENSLOCT00000009908.1; ENSLOCP00000009896.1; ENSLOCG00000008153.1.
DR GeneID; 102695654; -.
DR KEGG; loc:102695654; -.
DR CTD; 2849; -.
DR eggNOG; KOG3656; Eukaryota.
DR GeneTree; ENSGT00950000183001; -.
DR HOGENOM; CLU_009579_3_5_1; -.
DR InParanoid; W5MND7; -.
DR OMA; SWLGFHH; -.
DR OrthoDB; 5355548at2759; -.
DR Proteomes; UP000018468; Linkage group LG5.
DR Bgee; ENSLOCG00000008153; Expressed in brain and 2 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IBA:GO_Central.
DR GO; GO:0007189; P:adenylate cyclase-activating G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR CDD; cd15219; 7tmA_GPR26_GPR78-like; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR049579; GPR26/78-like.
DR PANTHER; PTHR24245; G-PROTEIN COUPLED RECEPTOR; 1.
DR PANTHER; PTHR24245:SF6; G-PROTEIN COUPLED RECEPTOR 26; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 126..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 22..295
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 338 AA; 38031 MW; 9210EBC3C79D3B31 CRC64;
MDTAEAIVSF LVVVIIIVSL LSNVLVLICF LYSPEIRKQV PGLFILNLTF CNLLMTVSNM
PLTLVGIINK GHPGGEGFCQ IVGFLDTFLT TNSMLSMAAL SIDRWIAVVF PLSYHSKMRH
RDAAVVLGYT WAHSMSFSTV AACLSWVGYH QLYASCTLCN ARASGSRTQF VIFTVAFHSL
TFLLSLIVLC VTYLKVLKVA RFHCKRIDII TMQTLVLLVD IHPSVRQRCL EEQRRRRQRA
TKKISTFIGT FVLCFAPYVI TRLVELFPAV PINPHWGAVS KCLAYSKAAC DPFVYSLLRY
QYRKTCSDIV NRILKRRSLN SSGVRGENGR NNIIQTTE
//
