ID W5MR85_LEPOC Unreviewed; 362 AA.
AC W5MR85;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=General transcription factor IIA subunit 1 {ECO:0000313|Ensembl:ENSLOCP00000010894.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000010894.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000010894.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TFIIA subunit 1 family.
CC {ECO:0000256|ARBA:ARBA00010059}.
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DR EMBL; AHAT01003915; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01003916; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5MR85; -.
DR Ensembl; ENSLOCT00000010910.1; ENSLOCP00000010894.1; ENSLOCG00000008922.1.
DR GeneTree; ENSGT00940000156726; -.
DR Proteomes; UP000018468; Linkage group LG7.
DR Bgee; ENSLOCG00000008922; Expressed in bone element and 13 other cell types or tissues.
DR GO; GO:0005672; C:transcription factor TFIIA complex; IEA:InterPro.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR CDD; cd07976; TFIIA_alpha_beta_like; 2.
DR Gene3D; 1.10.287.100; -; 1.
DR Gene3D; 2.30.18.10; Transcription factor IIA (TFIIA), beta-barrel domain; 1.
DR InterPro; IPR004855; TFIIA_asu/bsu.
DR InterPro; IPR009088; TFIIA_b-brl.
DR PANTHER; PTHR12694; TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1; 1.
DR PANTHER; PTHR12694:SF7; TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1; 1.
DR Pfam; PF03153; TFIIA; 2.
DR SMART; SM01371; TFIIA; 1.
DR SUPFAM; SSF47396; Transcription factor IIA (TFIIA), alpha-helical domain; 1.
DR SUPFAM; SSF50784; Transcription factor IIA (TFIIA), beta-barrel domain; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Transcription {ECO:0000256|ARBA:ARBA00023163}.
FT REGION 223..312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 234..254
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..312
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 362 AA; 40297 MW; D027C1E4DD3D749D CRC64;
IFLSVSLFQP KLYRSVIEDV INDVRELFLD EGVDEQVLME LRTLWESKLM QSKAVEGFHT
PQVIIPPAQQ VELNRQKLKL RVVHQNFIFF SFDVAPQQQV IVQDSKLLQH MNATGMSAAA
TAATLALPTG VSPYQQLITN QGQILQVVRA PNGAQYLIQP QQQVVLQQQV LPQMQPSGVQ
APVIQQVLTP LPGGIPQQTG VIIQPQQIVI AGNKVPQNAQ VMQAAPMAAP AGQSTAQVPP
QQQQQQQQQP AQPPMMLQVD GAGDTSSEED EEEEDEYDED EEEDKDKDGG EDGQVEEEPL
NSGDDVSDEE GQELFDTENV VVCQYDKIHR SKNKWKFHLK DGIMNLNGRD YVFSKAIGDA
EW
//
