ID W5MXR8_LEPOC Unreviewed; 259 AA.
AC W5MXR8;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Potassium channel tetramerization domain containing 2 {ECO:0000313|Ensembl:ENSLOCP00000013177.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000013177.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000013177.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AHAT01000205; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006635142.1; XM_006635079.2.
DR AlphaFoldDB; W5MXR8; -.
DR STRING; 7918.ENSLOCP00000013177; -.
DR Ensembl; ENSLOCT00000013205.1; ENSLOCP00000013177.1; ENSLOCG00000010755.1.
DR GeneID; 102692490; -.
DR KEGG; loc:102692490; -.
DR CTD; 23510; -.
DR eggNOG; KOG2715; Eukaryota.
DR GeneTree; ENSGT00940000158336; -.
DR HOGENOM; CLU_070830_0_1_1; -.
DR InParanoid; W5MXR8; -.
DR OMA; LCCQEGP; -.
DR OrthoDB; 54069at2759; -.
DR Proteomes; UP000018468; Linkage group LG10.
DR Bgee; ENSLOCG00000010755; Expressed in camera-type eye and 13 other cell types or tissues.
DR GO; GO:0031463; C:Cul3-RING ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0097602; F:cullin family protein binding; IBA:GO_Central.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR CDD; cd18389; BTB_POZ_KCTD2; 1.
DR Gene3D; 3.30.70.2000; -; 1.
DR Gene3D; 6.10.140.750; -; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR PANTHER; PTHR14958:SF22; BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD2; 1.
DR PANTHER; PTHR14958; POTASSIUM CHANNEL TETRAMERISATION DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF02214; BTB_2; 1.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT DOMAIN 69..171
FT /note="BTB"
FT /evidence="ECO:0000259|SMART:SM00225"
SQ SEQUENCE 259 AA; 29185 MW; E8F9487CE1C78C17 CRC64;
MAELHIVESG TGTIEHTEPR EIRNTVRLSS PTLMIPARSG LSSPGVSTRS SFGFPFKSNP
SSPEKPGSKW VRLNVGGTYF VTTKQTLCRE PKSFLSRLCQ EDPDLDSDKD ETGAYLIDRD
PTYFGPILNY LRHGKLIINK DLAEEGVLEE AEFYNIASLV RLVKERIRDN ENRTSQGPVK
HVYRVLQCQE EELTQMVSTM SDGWKFEQLI SIGSSYNYGN EDQAEFLCVV SRELNNSTNG
IVIEPSEKAK ILQERGSRM
//
