ID W5MY57_LEPOC Unreviewed; 454 AA.
AC W5MY57;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=SH2 domain containing 4A {ECO:0000313|Ensembl:ENSLOCP00000013316.1};
GN Name=SH2D4A {ECO:0000313|Ensembl:ENSLOCP00000013316.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000013316.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000013316.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AHAT01013396; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5MY57; -.
DR Ensembl; ENSLOCT00000013344.1; ENSLOCP00000013316.1; ENSLOCG00000010857.1.
DR GeneTree; ENSGT00940000157357; -.
DR Proteomes; UP000018468; Linkage group LG2.
DR Bgee; ENSLOCG00000010857; Expressed in ovary and 10 other cell types or tissues.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR PANTHER; PTHR14388:SF5; SH2 DOMAIN-CONTAINING PROTEIN 4A; 1.
DR PANTHER; PTHR14388; T CELL-SPECIFIC ADAPTER PROTEIN TSAD; 1.
DR Pfam; PF00017; SH2; 1.
DR PRINTS; PR00401; SH2DOMAIN.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50001; SH2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT DOMAIN 348..440
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 219..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 275..303
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 144..214
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 221..251
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 454 AA; 53134 MW; 3D83EF2C5E766C92 CRC64;
MLQQILADMY IEPELLAELN EEQKQILFFK MREEQVRRWK ERETKLEKQE LAQRKPKKAS
GKSISWLLGS DCDVWVWVMG EHPADKPYDQ ICDEIITERA RQQAQKEGEE IRYHHVCLER
AKKEEELVKR FSNTYLMDTQ MGIFDVWKKE AAEKEEQARR AAAEEKRRAE QELKQNLYSV
LMIIFCQRRE AEERRRAEED LRRLEEERTQ QIYMDLKEVQ QSVQKQDRDD PEWQETLQKS
KAADERRRSI AKQARADYKR LSLKAVERGR VAAMSKAFAG EDPTSKPSPP PKPKERSTAT
NNNVLHRKLA VRRTLSTSNK DVIIKWFKEE QIPLRAGYDK DQDCIAPWFH GVITRQGAEE
LLSTEGPGHF LIRVSEKITG YVLSYRCHEG YKHFLIDASD SSYSFLGVDQ LKHASLAELV
EYHKVEPITL SGGEQLLQPS GQKCENPDYS ELFS
//
