ID W5MZZ0_LEPOC Unreviewed; 309 AA.
AC W5MZZ0;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Fibrinogen C-terminal domain-containing protein {ECO:0000259|PROSITE:PS51406};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000013949.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000013949.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; AHAT01000276; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01000277; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01000278; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5MZZ0; -.
DR Ensembl; ENSLOCT00000013978.1; ENSLOCP00000013949.1; ENSLOCG00000011332.1.
DR GeneTree; ENSGT00940000163282; -.
DR OMA; RGPRSCK; -.
DR Proteomes; UP000018468; Linkage group LG10.
DR Bgee; ENSLOCG00000011332; Expressed in bone element and 13 other cell types or tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR CDD; cd00087; FReD; 1.
DR Gene3D; 3.90.215.10; Gamma Fibrinogen, chain A, domain 1; 1.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR036056; Fibrinogen-like_C.
DR InterPro; IPR014716; Fibrinogen_a/b/g_C_1.
DR InterPro; IPR002181; Fibrinogen_a/b/g_C_dom.
DR InterPro; IPR020837; Fibrinogen_CS.
DR NCBIfam; NF040941; GGGWT_bact; 1.
DR PANTHER; PTHR19143; FIBRINOGEN/TENASCIN/ANGIOPOEITIN; 1.
DR PANTHER; PTHR19143:SF448; FICOLIN-2; 1.
DR Pfam; PF01391; Collagen; 1.
DR Pfam; PF00147; Fibrinogen_C; 1.
DR SMART; SM00186; FBG; 1.
DR SUPFAM; SSF56496; Fibrinogen C-terminal domain-like; 1.
DR PROSITE; PS00514; FIBRINOGEN_C_1; 1.
DR PROSITE; PS51406; FIBRINOGEN_C_2; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Collagen {ECO:0000256|ARBA:ARBA00023119};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Immunity {ECO:0000256|ARBA:ARBA00022859};
KW Innate immunity {ECO:0000256|ARBA:ARBA00022588};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..309
FT /note="Fibrinogen C-terminal domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004866951"
FT DOMAIN 90..309
FT /note="Fibrinogen C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51406"
FT REGION 45..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 309 AA; 33729 MW; A3D034B2CE308415 CRC64;
VSGSIFIVSM FVTVASGGEN TCPELKVVGL NDKDRLTILQ GCPGHPGIPG APGAPGMKGG
EGPRGVAGEP GAFGKIGPAG SKGQKGEPGD QRSKGARNCK ELLDQGNYIS GWYTVRTVGD
KDIRVFCDMD TDGGGWLVFQ RRMDGSVDFF RDWASYKRGF GNQQSEFWLG NDHIHSLTSS
EGDYELRIDF KDFDNAATFA KYSNFLVTGE SENYKLLLGN FEAGSAGDSF TYHNSMPFSA
KDRDNDSHDN SCSTMFKGGW WYGKCHQANL NGLYLGGSHE SHANGINWLT GKGQKYSYKY
CDMKIRPRP
//
