ID W5N193_LEPOC Unreviewed; 442 AA.
AC W5N193;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=RUN domain-containing protein 3A {ECO:0000256|ARBA:ARBA00034858};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000014402.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000014402.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RUNDC3 family.
CC {ECO:0000256|ARBA:ARBA00034727}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AHAT01023007; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01023008; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5N193; -.
DR STRING; 7918.ENSLOCP00000014402; -.
DR Ensembl; ENSLOCT00000014431.1; ENSLOCP00000014402.1; ENSLOCG00000011714.1.
DR eggNOG; KOG4381; Eukaryota.
DR GeneTree; ENSGT00940000158922; -.
DR HOGENOM; CLU_045987_0_0_1; -.
DR InParanoid; W5N193; -.
DR OMA; FWEYVRL; -.
DR Proteomes; UP000018468; Linkage group LG15.
DR Bgee; ENSLOCG00000011714; Expressed in brain and 7 other cell types or tissues.
DR GO; GO:0010753; P:positive regulation of cGMP-mediated signaling; IBA:GO_Central.
DR CDD; cd17699; RUN_RUNDC3A; 1.
DR Gene3D; 1.20.58.900; -; 1.
DR InterPro; IPR004012; Run_dom.
DR InterPro; IPR037213; Run_dom_sf.
DR InterPro; IPR047338; RUN_RUNDC3A.
DR InterPro; IPR047340; RUNDC3A_B.
DR PANTHER; PTHR46251; RUN DOMAIN-CONTAINING 3 PROTEIN RUNDC3; 1.
DR PANTHER; PTHR46251:SF4; RUN DOMAIN-CONTAINING PROTEIN 3A; 1.
DR Pfam; PF02759; RUN; 1.
DR SMART; SM00593; RUN; 1.
DR SUPFAM; SSF140741; RUN domain-like; 1.
DR PROSITE; PS50826; RUN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT DOMAIN 60..192
FT /note="RUN"
FT /evidence="ECO:0000259|PROSITE:PS50826"
FT COILED 271..320
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 442 AA; 49935 MW; D35D6A81C5B74C84 CRC64;
RCGSAPSWME SSCLQSAMAM GLSSKKASCR SVAVERKNLI TVCRFSVKTL LEKYTAEPID
DSSEEFINFA AILEQILSHR FKGPASWFSY DGQRSFWDYI RVACSKVQNN CVSSIENMEN
INSSRAKGRA WVRVALMEKR LSEYIATALR DTRTTRRFYD DGAIMLREES TVLTGMLIGL
SAIDFSFCLK GEVLDGKTPA VIDYTPYLKF TQSYDYMSDD DDRNSVDSST SDDSIPDHPY
IPLVTDEESW SRKCRKMEQK YKIVYAQKGY LEELVRLRES QLKNLEAENK RLTLRLEEAR
LQSQQEKKEL EGIVLELQEQ LTGLIPCDSN NLSKEMTIPL VNQWPSLRTF NNQEDVKLFR
RRSFHSVEQL SAEISLDSDS QKTDGKQNGE TWCTTGKDYT PSMLGLCGSL ASLPSCKSLA
SLKSSECLVT ISTEASPALS PS
//
