ID W5NNF9_LEPOC Unreviewed; 561 AA.
AC W5NNF9;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Potassium voltage-gated channel subfamily A member 10 {ECO:0000313|Ensembl:ENSLOCP00000022168.1};
GN Name=KCNA10 {ECO:0000313|Ensembl:ENSLOCP00000022168.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000022168.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000022168.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AHAT01014334; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015197629.1; XM_015342143.1.
DR AlphaFoldDB; W5NNF9; -.
DR STRING; 7918.ENSLOCP00000022168; -.
DR Ensembl; ENSLOCT00000022209.1; ENSLOCP00000022168.1; ENSLOCG00000018067.1.
DR GeneID; 102689659; -.
DR KEGG; loc:102689659; -.
DR CTD; 3744; -.
DR eggNOG; KOG1545; Eukaryota.
DR GeneTree; ENSGT00940000159534; -.
DR HOGENOM; CLU_011722_4_0_1; -.
DR InParanoid; W5NNF9; -.
DR OMA; MEVAMVD; -.
DR OrthoDB; 1478695at2759; -.
DR Proteomes; UP000018468; Linkage group LG3.
DR GO; GO:0008076; C:voltage-gated potassium channel complex; IBA:GO_Central.
DR GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:GO_Central.
DR GO; GO:0071805; P:potassium ion transmembrane transport; IBA:GO_Central.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR CDD; cd18409; BTB_POZ_KCNA10; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR InterPro; IPR003972; K_chnl_volt-dep_Kv1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR11537:SF44; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 10; 1.
DR PANTHER; PTHR11537; VOLTAGE-GATED POTASSIUM CHANNEL; 1.
DR Pfam; PF02214; BTB_2; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01491; KVCHANNEL.
DR PRINTS; PR01496; SHAKERCHANEL.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 251..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 482..503
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 120..220
FT /note="BTB"
FT /evidence="ECO:0000259|SMART:SM00225"
FT REGION 45..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 516..561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 526..561
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 561 AA; 63424 MW; 2534BDA191C031EB CRC64;
MCSWRVMEVA LVNFENTDDI EIGMGDSGDP EYSGYMSEKT ALTTSIPDQS HGNNHLPNQQ
PQSSQTTQSR RGRPSSASLM SNWKLLLNSE VTQNETIFSR LAKECGEDFL DKGGLDDGDQ
KVIINIAGLR FETQLKTLDQ FPETLLGDPQ KRMEYFDPMR NEYFFDRNRP SFDGILYYYQ
SGGKIRRPAN VPIDVFADEI IFYELGNEAM DQFREDEGFI KDVEVALPTN EIYRQFWLLF
EYPESSNAAR AVALVSVFVI IISIVIFCLE TLPEFREDLE FIPRVVQLLN QTQEESTSAP
FPSPTPKTIS KALSDPFFVI ETACIVWFFF ELCVRFLVCP SRQEFFRNIM NIIDIISIIP
YFVTLITELL TDPDTSAGQN MSLAILRIIR LVRVFRIFKL SRHSKGLQIL GQTLKASMRE
LGLLIFFLFI GVILFSSAAY FAEVDEPQTQ FTSIPEGFWW AVVTMTTVGY GDMCPITLGG
KMVGTLCAIA GVLTIALPVP VIVSNFNYFY HRETENEDKP SLPSELEASL KSSVTAKQGS
TTSLNKPNGT WMNDKSKNGK P
//
