ID W5P820_SHEEP Unreviewed; 245 AA.
AC W5P820;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOARP00000006574.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000006574.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000006574.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000006574.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000006574.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AMGL01026246; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5P820; -.
DR SMR; W5P820; -.
DR STRING; 9940.ENSOARP00000006574; -.
DR PaxDb; 9940-ENSOARP00000006574; -.
DR Ensembl; ENSOART00000006677.1; ENSOARP00000006574.1; ENSOARG00000006138.1.
DR eggNOG; KOG4295; Eukaryota.
DR HOGENOM; CLU_092095_0_0_1; -.
DR OMA; GFCPHKP; -.
DR Proteomes; UP000002356; Chromosome 13.
DR Bgee; ENSOARG00000006138; Expressed in spleen.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd00109; Kunitz-type; 1.
DR Gene3D; 4.10.75.10; Elafin-like; 3.
DR Gene3D; 4.10.410.10; Pancreatic trypsin inhibitor Kunitz domain; 1.
DR InterPro; IPR036645; Elafin-like_sf.
DR InterPro; IPR002223; Kunitz_BPTI.
DR InterPro; IPR036880; Kunitz_BPTI_sf.
DR InterPro; IPR020901; Prtase_inh_Kunz-CS.
DR InterPro; IPR008197; WAP_dom.
DR InterPro; IPR042931; WFDC8/12/15B-like.
DR PANTHER; PTHR47769; WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 8; 1.
DR PANTHER; PTHR47769:SF1; WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 8; 1.
DR Pfam; PF00014; Kunitz_BPTI; 1.
DR Pfam; PF00095; WAP; 3.
DR PRINTS; PR00003; 4DISULPHCORE.
DR PRINTS; PR00759; BASICPTASE.
DR SMART; SM00131; KU; 1.
DR SMART; SM00217; WAP; 3.
DR SUPFAM; SSF57362; BPTI-like; 1.
DR SUPFAM; SSF57256; Elafin-like; 3.
DR PROSITE; PS00280; BPTI_KUNITZ_1; 1.
DR PROSITE; PS50279; BPTI_KUNITZ_2; 1.
DR PROSITE; PS51390; WAP; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..42
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 43..245
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004868577"
FT DOMAIN 48..95
FT /note="WAP"
FT /evidence="ECO:0000259|PROSITE:PS51390"
FT DOMAIN 99..149
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 151..197
FT /note="WAP"
FT /evidence="ECO:0000259|PROSITE:PS51390"
FT DOMAIN 198..244
FT /note="WAP"
FT /evidence="ECO:0000259|PROSITE:PS51390"
SQ SEQUENCE 245 AA; 27632 MW; DC9E06080998E75A CRC64;
VPNPCPLVFP FHRHLPFHSS TFSWRNVALL LLFSLSLEQT SASPSYRVKK KPGECPQERI
TCSSKAPDLC KTDFNCDEHL KCCSFACGKK CMDPYEEPCL LPLDQGQCKN TVKHWYFNIK
QRICKPFFYG GCLGNANNFP KKEDCMKACS SVVKDGQCPL FPFKNRMECS ALCKSDYDCP
LNEKCCESMC GFDCAMAWTV KAGFCPNKPP VCSMIDRPKC LQDNDCPLTT KCCSRCGLKC
LEPLK
//
