ID W5PJA4_SHEEP Unreviewed; 969 AA.
AC W5PJA4;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=SP-RING-type domain-containing protein {ECO:0000259|PROSITE:PS51044};
GN Name=ZMIZ1 {ECO:0000313|Ensembl:ENSOARP00000010525.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000010525.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000010525.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000010525.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000010525.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AMGL01071664; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01071665; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01071666; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01071667; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5PJA4; -.
DR SMR; W5PJA4; -.
DR STRING; 9940.ENSOARP00000010525; -.
DR PaxDb; 9940-ENSOARP00000010525; -.
DR Ensembl; ENSOART00000010681.1; ENSOARP00000010525.1; ENSOARG00000009814.1.
DR eggNOG; KOG2169; Eukaryota.
DR HOGENOM; CLU_009461_1_0_1; -.
DR OMA; PPMAMNQ; -.
DR Proteomes; UP000002356; Chromosome 25.
DR Bgee; ENSOARG00000009814; Expressed in cerebellum and 51 other cell types or tissues.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0060255; P:regulation of macromolecule metabolic process; IEA:UniProt.
DR CDD; cd16822; SP-RING_ZMIZ1; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR004181; Znf_MIZ.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR10782; ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10782:SF7; ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF02891; zf-MIZ; 1.
DR PROSITE; PS51044; ZF_SP_RING; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00452}.
FT DOMAIN 630..711
FT /note="SP-RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51044"
FT REGION 19..68
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 268..378
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 395..435
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 772..969
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..68
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..314
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 345..362
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 363..378
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 416..435
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 784..801
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 848..879
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 880..899
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 904..920
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 952..969
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 969 AA; 104092 MW; A465079DFFD9F0A0 CRC64;
AALLSSWCEE LGRLLLLRHQ KSRQSDPPGK LPMQPPLNSM SSMKPTLSHS DGSFPYDSVP
WQQNTNQPPG SLSVVTTVWG VTNTSQSQVL GNPMANANNP MNPGGNPMAS GMTTSNPGLN
SPQFAGQQQQ FSAKAGPTQP YIQQSMYGRP NYPGSGGFGA SYPGGPNAPA GMGVPPHTRP
PADFTQPAAA AAAAAVAAAV AAAAPPATAT ATATVAALQE TQNKDINQYG PVCSSFQMGP
TQAYNSQFMN QPGPRGPASM GGSMNPANMA AGIKPSGMSG PPMGMNQPRP PGISPFGTHG
QRMPQQTYPG PRPQSLPIQS IKRPYPGEPN YGNQQYGPNS QFPTQPGQYP TPNPPRPLTS
PNYPGQRMPS QPSTGQYPPP TVNMGQYYKP EQFNGGVCTG PAGKKTHGGT KRPPRPVPVA
NYPHSPTPPM PPGSSIPPYL SPSQDVKPPF PPDIKPNMSA LPPPPVNHTA RLLWPCSHTH
ALEHNLAVSN HVFHLRPTVH QTLMWRSDLE LQFKCYHHED RQMNTNWPAS VQVSVNATPL
TIERGDNKTS HKPLHLKPVC QPLSAPWGVG SRGCCYSHLF VLQLVHRPSV RSVLQGLLKK
RLLPAEHCIT KIKRNFSSVA ASSGNTTLNG EDGVEQTAIK VSLKCPITFR RIQLPARGHD
CKHVQCFDLE SYLQLNCERG TWRCPVCNKT ALLEGLEVDQ YMWGILNAIQ HSEFEEVTID
PTCSWRPVPI KSDLHIKDDP DGIPSKRFKT MSPSQMIMPN VMEMIAALGP GPSPYPLPPP
PGSANSNDYS SQGNNYQGHG NFDFPHGNPG GTSMNDFMHG PPQLSHPPDM PNNMATLEKP
LSHPMQETMP HAGSSDQPHP SIQQGLHVPH PSSQSGPPLH HSGAPPPPSQ PPRQPPQAAP
GNHPHSDLTF NPSSALEGQA GAQGASDMPE PSLDLLPELT NPDELLSYLD PPDLPSNSND
DLLSLFENN
//
