ID W5PMG5_SHEEP Unreviewed; 204 AA.
AC W5PMG5;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=WIBG Mago-binding domain-containing protein {ECO:0000259|SMART:SM01273};
GN Name=PYM1 {ECO:0000313|Ensembl:ENSOARP00000011640.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000011640.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000011640.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000011640.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000011640.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Interacts (via N-terminus) with magoh and rbm8a; the
CC interaction is direct. Associates (eIF2A-like region) with the 40S
CC ribosomal subunit and the 48S preinitiation complex.
CC {ECO:0000256|ARBA:ARBA00025900}.
CC -!- SIMILARITY: Belongs to the pym family. {ECO:0000256|ARBA:ARBA00009394}.
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DR EMBL; AMGL01081607; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5PMG5; -.
DR SMR; W5PMG5; -.
DR STRING; 9940.ENSOARP00000011640; -.
DR PaxDb; 9940-ENSOARP00000011640; -.
DR Ensembl; ENSOART00000011806.1; ENSOARP00000011640.1; ENSOARG00000010856.1.
DR eggNOG; KOG4325; Eukaryota.
DR OMA; IPGCADS; -.
DR Proteomes; UP000002356; Chromosome 3.
DR Bgee; ENSOARG00000010856; Expressed in gastric lymph node and 57 other cell types or tissues.
DR ExpressionAtlas; W5PMG5; baseline.
DR GO; GO:1903259; P:exon-exon junction complex disassembly; IEA:InterPro.
DR InterPro; IPR039333; PYM1.
DR InterPro; IPR015362; WIBG_mago-bd.
DR InterPro; IPR036348; WIBG_N_sf.
DR PANTHER; PTHR22959:SF0; PARTNER OF Y14 AND MAGO; 1.
DR PANTHER; PTHR22959; PYM PROTEIN; 1.
DR Pfam; PF09282; Mago-bind; 1.
DR SMART; SM01273; Mago-bind; 1.
DR SUPFAM; SSF101931; Pym (Within the bgcn gene intron protein, WIBG), N-terminal domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002356}.
FT DOMAIN 12..38
FT /note="WIBG Mago-binding"
FT /evidence="ECO:0000259|SMART:SM01273"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 55..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 116..145
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 204 AA; 22837 MW; 63CB93CFDCF9D7FD CRC64;
IRVTLQPNSP ISGKYIASTQ RPDGTWRKQR RVKEGYVPQE EVPVYENKYV KFFKSKPELP
PGLSPEATAP ISASRPEGGE PALSKTAKRN LKRKEKRRQQ QEKGEAEALS RTLEKVSLGE
TAQVPSAPQA SRAVPTAASD QSDSATTTEK AKKIKNLKKK LRQVEELQQR IQAGEISQPS
KEQLEKLARR RALEEELEDL ELGL
//
