ID W5Q747_SHEEP Unreviewed; 651 AA.
AC W5Q747;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Suppressor of forked domain-containing protein {ECO:0000259|Pfam:PF05843};
GN Name=CSTF3 {ECO:0000313|Ensembl:ENSOARP00000018539.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000018539.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000018539.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000018539.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000018539.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AMGL01032835; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01032836; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5Q747; -.
DR SMR; W5Q747; -.
DR STRING; 9940.ENSOARP00000018539; -.
DR PaxDb; 9940-ENSOARP00000018539; -.
DR Ensembl; ENSOART00000018801.1; ENSOARP00000018539.1; ENSOARG00000017271.1.
DR eggNOG; KOG1914; Eukaryota.
DR HOGENOM; CLU_007630_3_1_1; -.
DR OMA; CFRGPFV; -.
DR Proteomes; UP000002356; Chromosome 15.
DR Bgee; ENSOARG00000017271; Expressed in major salivary gland and 54 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031124; P:mRNA 3'-end processing; IEA:InterPro.
DR Gene3D; 1.25.40.1040; -; 1.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR045243; Rna14-like.
DR InterPro; IPR008847; Suf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR19980:SF0; CLEAVAGE STIMULATION FACTOR SUBUNIT 3; 1.
DR PANTHER; PTHR19980; RNA CLEAVAGE STIMULATION FACTOR; 1.
DR Pfam; PF05843; Suf; 1.
DR SMART; SM00386; HAT; 9.
DR SUPFAM; SSF48452; TPR-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002356}.
FT DOMAIN 309..583
FT /note="Suppressor of forked"
FT /evidence="ECO:0000259|Pfam:PF05843"
FT REGION 618..639
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 619..636
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 651 AA; 75140 MW; A42A48339D09447C CRC64;
MSGDGATEQI KAKNYDKVEK LFQRCLMKVL HIDLWKCYLS YVRETKGKLP SYKEKMAQAY
DFALDKIGME IMSYQIWVDY INFLKGVEAV GSYAENQRIT AVRRVYQRGC VNPMINIEQL
WRDYNKYEEG INIHLAKKMI EDRSRDYMNA RRVAKEYETV MKGLDRNAPS VPPQNTPQEA
QQVDMWKKYI QWEKSNPLRT EDQTLITKRV MFAYEQCLLV LGHHPDIWYE AAQYLEQSSK
LLAEKGDMNN AKLFSDEAAN IYERAISTLL KKNMLLYFAY ADYEESRMKY EKVHSIYNRL
LAIEDIDPTL VYIQYMKFAR RAEGIKSGRM IFKKAREDTR TRHHVYVTAA LMEYYCSKDK
SVAFKIFELG LKKYGDIPEY VLAYIDYLSH LNEDNNTRVL FERVLTSGSL PPEKSGEIWA
RFLAFESNIG DLASILKVEK RRFTAFKEEY EGKETALLVD RYKFMDLYPC SASELKALGY
KDVSRAKLAA IIPDPVVAPS IVPVLKDEVD RKPEYPKPDT QQMIPFQPRH LAPPGLHPVP
GGVFPVPPAA VVLMKLLPPP ICFQGPFVQV DELMEIFRRC KIPNTVEEAV RIITGGAPEL
AVEGNGPVES NAVLTKAVKR PNEDSDEDEE KGAVVPPVHD IYRARQQKRI R
//
