ID   W5QAE2_SHEEP            Unreviewed;       785 AA.
AC   W5QAE2;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   RecName: Full=N-acetyltransferase domain-containing protein {ECO:0000259|PROSITE:PS51186};
GN   Name=KAT14 {ECO:0000313|Ensembl:ENSOARP00000019685.1};
OS   Ovis aries (Sheep).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Caprinae; Ovis.
OX   NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000019685.1, ECO:0000313|Proteomes:UP000002356};
RN   [1] {ECO:0000313|Ensembl:ENSOARP00000019685.1, ECO:0000313|Proteomes:UP000002356}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000019685.1,
RC   ECO:0000313|Proteomes:UP000002356};
RX   PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA   Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA   Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA   Wang W., Xun X.;
RT   "The sheep genome reference sequence: a work in progress.";
RL   Anim. Genet. 41:449-453(2010).
RN   [2] {ECO:0000313|Ensembl:ENSOARP00000019685.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AMGL01024932; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; W5QAE2; -.
DR   SMR; W5QAE2; -.
DR   STRING; 9940.ENSOARP00000019685; -.
DR   PaxDb; 9940-ENSOARP00000019685; -.
DR   Ensembl; ENSOART00000019958.1; ENSOARP00000019685.1; ENSOARG00000018339.1.
DR   eggNOG; KOG3138; Eukaryota.
DR   HOGENOM; CLU_022855_0_0_1; -.
DR   OMA; PRRNWPW; -.
DR   Proteomes; UP000002356; Chromosome 13.
DR   Bgee; ENSOARG00000018339; Expressed in pituitary gland and 54 other cell types or tissues.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   CDD; cd04301; NAT_SF; 1.
DR   Gene3D; 3.40.630.30; -; 1.
DR   Gene3D; 3.90.980.20; -; 1.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR000182; GNAT_dom.
DR   PANTHER; PTHR20916; CYSTEINE AND GLYCINE-RICH PROTEIN 2 BINDING PROTEIN; 1.
DR   PANTHER; PTHR20916:SF26; CYSTEINE-RICH PROTEIN 2-BINDING PROTEIN; 1.
DR   Pfam; PF00583; Acetyltransf_1; 1.
DR   SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR   PROSITE; PS51186; GNAT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002356}.
FT   DOMAIN          641..785
FT                   /note="N-acetyltransferase"
FT                   /evidence="ECO:0000259|PROSITE:PS51186"
FT   REGION          1..33
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          245..298
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          315..346
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          387..460
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        9..27
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        246..279
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        404..458
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   785 AA;  89006 MW;  3CADA5B8FC3A6505 CRC64;
     MEGSIHLSGL ISRHDDEATR TSTSEGLEEG EVEGETLLIV ESEDQASVDL SHDHSGDSLN
     SDEGDVSWME EQLSYFCDKC QKWIPASQLR EQLSYLKGDN FFRFTCSDCS EDGKEQYERL
     KLTWQQVVVL AMYNLSLEGS GRQGYFRWKE DICAFIEKHW TFLLGNRKKT STWWSTVAGC
     LSVGSPMYFR SGAQEFGEPG WWKLVHNRPP TLKPEGDKLS ASALKVKAAS KPTLDPIITV
     EGLRKRASRN PVESAMELKE KRSRTQEAKD IRRAQKEAAG FADRSSSSTP VKFISRGRRP
     DMILEKGEVI DFSSLSSSDR TPLTSPSPSP SLDFSAPGTP ASHSATPSLL SEADLIPDVM
     PPQALFHDDD EMEGDGVIDP GMEYVPPPAG AATSGTGLGG RKKVRAPEQI KQEVESEEEK
     PDRMDIDSED TDSNTSLQTR AREKRKPVLE KDRKPKGPKF TPVSIYEEKL LLRRLEACPG
     AVAMTPEARR LKRKLIVRQA KRDRGLPLFD LDQVVNAALL LVDGIYGAKD GGVSRLPAGQ
     ATYRTTCQDF RILDRYQTAL PSRKGFRHQS TKFLYRLVGS EDMAVDQSIV SPYTSRILKP
     YIRFWRRDYE TKPPKLQLLS QIRSHLHRGD PHWTPEPDAP LDYCYVRPNH IPTINSMCQE
     FFWPGVDLSE CLQYPDFSVV VLYKKVIIAF GFMVPDVKYN EAYISFLFVH PDWRRAGIAT
     FMIYHLIQTC MGKDVTLHVS ASNPAMLLYQ KFGFKTEEYV LDFYDKYYPL ESTECKHAFF
     LRLRR
//