ID W5TEZ8_9NOCA Unreviewed; 549 AA.
AC W5TEZ8;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=HNH nuclease domain-containing protein {ECO:0000259|SMART:SM00507};
GN ORFNames=NONO_c30880 {ECO:0000313|EMBL:AHH17875.1};
OS Nocardia nova SH22a.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1415166 {ECO:0000313|EMBL:AHH17875.1, ECO:0000313|Proteomes:UP000019150};
RN [1] {ECO:0000313|EMBL:AHH17875.1, ECO:0000313|Proteomes:UP000019150}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SH22a {ECO:0000313|EMBL:AHH17875.1};
RX PubMed=24747905;
RA Luo Q., Hiessl S., Poehlein A., Daniel R., Steinbuchel A.;
RT "Insights into the Microbial Degradation of Rubber and Gutta-Percha by
RT Analysis of the Complete Genome of Nocardia nova SH22a.";
RL Appl. Environ. Microbiol. 80:3895-3907(2014).
CC -!- SIMILARITY: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.
CC {ECO:0000256|ARBA:ARBA00023450}.
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DR EMBL; CP006850; AHH17875.1; -; Genomic_DNA.
DR AlphaFoldDB; W5TEZ8; -.
DR STRING; 1415166.NONO_c30880; -.
DR KEGG; nno:NONO_c30880; -.
DR PATRIC; fig|1415166.3.peg.3166; -.
DR eggNOG; COG1403; Bacteria.
DR HOGENOM; CLU_022065_0_0_11; -.
DR OrthoDB; 3513062at2; -.
DR Proteomes; UP000019150; Chromosome.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00085; HNHc; 1.
DR Gene3D; 1.10.30.50; -; 1.
DR InterPro; IPR003870; DUF222.
DR InterPro; IPR002711; HNH.
DR InterPro; IPR003615; HNH_nuc.
DR Pfam; PF02720; DUF222; 1.
DR Pfam; PF01844; HNH; 1.
DR SMART; SM00507; HNHc; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000019150}.
FT DOMAIN 361..413
FT /note="HNH nuclease"
FT /evidence="ECO:0000259|SMART:SM00507"
FT REGION 476..549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 505..522
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 549 AA; 59146 MW; CBDA3146F3C87CB8 CRC64;
MHSIGGEIAE RVAEPALMAV SDLLERSLTP LSDGDLVAAM RDVETCARRL AAMQHRLLIE
AEERSLPSRT GAKTVKRFLM QTLRLSSADA GSRVNAAQWV GTFHDLDGEL RDPQLPCTAG
ALTSGEVSID HVRGIVTVMN RVPRGVSDAD REAAEQILAE FARSGSPDDI DKVGDRILAH
LDPDGRLTTD LDRARMRGVM IGRQRSDGMS PIRGDIDPVL RALLDPLLAK YARPGVCNFE
DPNSPAVEID TADPTAIAEA ARADHRTPAQ RNHDALTAIL RSGLVAEDLG RHRGMPVTTV
LTMKLEDLER DSGVASTATG TVVPIREALQ LAEHSRPYLA VFDHAGLPLH LGRMKRLASP
AQRLALIAAL RGCSRPGCDA PASLCAAHHI RDFAAGGRTD IENLALACDA CHALIHNGPG
GWKTTTAGPD SRHPGRTAWI APEHIDPTRT PRINHRHHAD ELLATIIARI HVRDDLERQQ
RRQHAHKQHQ RRPAAHPHPP DTTAPCHNPT TGSGQSTAPS VIPGSGRGAP SRGHRRRHGV
LSGQLGTGS
//
