ID W5UBD0_ICTPU Unreviewed; 309 AA.
AC W5UBD0;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Mitochondrial fission regulator {ECO:0000256|RuleBase:RU369053};
GN Name=mtfr1l {ECO:0000313|EMBL:AHH39316.1,
GN ECO:0000313|RefSeq:XP_053538451.1, ECO:0000313|RefSeq:XP_053538452.1,
GN ECO:0000313|RefSeq:XP_053538453.1, ECO:0000313|RefSeq:XP_053538454.1,
GN ECO:0000313|RefSeq:XP_053538455.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|EMBL:AHH39316.1};
RN [1] {ECO:0000313|EMBL:AHH39316.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Mixed {ECO:0000313|EMBL:AHH39316.1};
RX PubMed=23127152; DOI=10.1186/1471-2164-13-595;
RA Liu S., Zhang Y., Zhou Z., Waldbieser G., Sun F., Lu J., Zhang J.,
RA Jiang Y., Zhang H., Wang X., Rajendran K.V., Khoo L., Kucuktas H.,
RA Peatman E., Liu Z.;
RT "Efficient assembly and annotation of the transcriptome of catfish by RNA-
RT Seq analysis of a doubled haploid homozygote.";
RL BMC Genomics 13:595-595(2012).
RN [2] {ECO:0000313|RefSeq:XP_053538451.1, ECO:0000313|RefSeq:XP_053538452.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_053538451.1,
RC ECO:0000313|RefSeq:XP_053538452.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Plays a role in mitochondrial aerobic respiration. Regulates
CC mitochondrial organization and fission.
CC {ECO:0000256|RuleBase:RU369053}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000256|RuleBase:RU369053}.
CC -!- SIMILARITY: Belongs to the MTFR1 family.
CC {ECO:0000256|ARBA:ARBA00005807, ECO:0000256|RuleBase:RU369053}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JT411132; AHH39316.1; -; mRNA.
DR RefSeq; XP_053538451.1; XM_053682476.1.
DR RefSeq; XP_053538452.1; XM_053682477.1.
DR RefSeq; XP_053538453.1; XM_053682478.1.
DR RefSeq; XP_053538454.1; XM_053682479.1.
DR RefSeq; XP_053538455.1; XM_053682480.1.
DR KEGG; ipu:108269592; -.
DR Proteomes; UP000221080; Chromosome 9.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR GO; GO:0009060; P:aerobic respiration; IEA:UniProtKB-UniRule.
DR GO; GO:0000266; P:mitochondrial fission; IEA:UniProtKB-UniRule.
DR InterPro; IPR007972; Mtfr1.
DR PANTHER; PTHR14215:SF3; MITOCHONDRIAL FISSION REGULATOR 1-LIKE; 1.
DR PANTHER; PTHR14215; PROTEIN OF UNKNOWN FUNCTION DUF729; 1.
DR Pfam; PF05308; Mito_fiss_reg; 1.
PE 2: Evidence at transcript level;
KW Mitochondrion {ECO:0000256|RuleBase:RU369053}.
FT REGION 191..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..213
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 309 AA; 34731 MW; 1DD616598B7D2019 CRC64;
MDTEAEVIPI WQNKPHGATR SVVRRIGSTL PLKPCPRACF QELPGLNPLR HTDGPLVPTL
ADIAWIAADE EETYARVRSD TRPFRQEWRP TPLMVLHRNS SVPNFRREGK RMEGLRKPGA
TALNRATALQ DELSRLRAQI AKIVAGETDS NPITPDLLSP DDTTVGFSMA PFEAAAFHPL
PTASFVISDV TEVDEEEEEE EEELEDESEV PELEPDPVPP VCMTASATFD LDRPTMDFRE
AEEDTVSLSK STSFADVKDI LRDMNRMKMS KDRYSRGCTS LMEEDSATLI SEALRKKFTL
RDEDVNMKK
//
