ID W5UIC3_ICTPU Unreviewed; 873 AA.
AC W5UIC3;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Putative G-protein coupled receptor 133 {ECO:0000313|EMBL:AHH41842.1};
GN Name=GPR133 {ECO:0000313|EMBL:AHH41842.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|EMBL:AHH41842.1};
RN [1] {ECO:0000313|EMBL:AHH41842.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Mixed {ECO:0000313|EMBL:AHH41842.1};
RX PubMed=23127152; DOI=10.1186/1471-2164-13-595;
RA Liu S., Zhang Y., Zhou Z., Waldbieser G., Sun F., Lu J., Zhang J.,
RA Jiang Y., Zhang H., Wang X., Rajendran K.V., Khoo L., Kucuktas H.,
RA Peatman E., Liu Z.;
RT "Efficient assembly and annotation of the transcriptome of catfish by RNA-
RT Seq analysis of a doubled haploid homozygote.";
RL BMC Genomics 13:595-595(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JT415862; AHH41842.1; -; mRNA.
DR AlphaFoldDB; W5UIC3; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.60.220.50; -; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR046338; GAIN_dom_sf.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR017983; GPCR_2_secretin-like_CS.
DR InterPro; IPR000203; GPS.
DR PANTHER; PTHR12011; ADHESION G-PROTEIN COUPLED RECEPTOR; 1.
DR PANTHER; PTHR12011:SF216; ADHESION G-PROTEIN COUPLED RECEPTOR D1; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR Pfam; PF01825; GPS; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR PRINTS; PR00249; GPCRSECRETIN.
DR SMART; SM00303; GPS; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00650; G_PROTEIN_RECEP_F2_2; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR PROSITE; PS50221; GPS; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:AHH41842.1};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 568..591
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 603..622
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 634..651
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 672..691
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 711..737
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 758..779
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 785..808
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 565..809
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
SQ SEQUENCE 873 AA; 96722 MW; A3A22106E7A3F3EC CRC64;
MDFLYKVLNF STFVSVLQVL GDQAVPSKHP GLDVLATASH YWPLDDVDGI RSLRDQIGNR
TDIVEGVVNK GIYLNGDRGA TFLHFGNYKN SCISDPTLCG PQGITFSFFW KNQESHSRFA
VMSGGKIISN GFSVYTNPLG GYVEFYTRRN SQRWKANINL PGPFWTHILF TWTLKDGLKI
YINGTFNISD PKGDVSQNYG NTYADLVIGT GSSHSYGHYV TASFDEFVIW ERALSAKEIC
LYYKAAIGED VVYPPTTESP SSARATTDAL LQETAASPHS TVSNFTEIHD SVSMSLQGFL
QSSFILPNRT IPKDTAHNLT QSFLKSVDEV IASSSWREDE ESTPVISGLI DTVDKVMGHM
VSNLEAKPNS LVAFGGKSYV ADYALMKIPQ SYNMQNYRFP TQGKNYISVP GEAFATESQT
TIVGLFYHSM HNHYKQISPL RTRIDEAAGF KDHKIQVASY LISLKVEPSP ALSVNLSSEP
LIRIMLTHQL SKEQQLQAMN ESNKVFLYCA FLDYSSKEGV WSDNGCLRAG GNLSYSVCVC
NHLTNFAILM QVVPVELSKS HQVALSTITY VGCSISIFCL AITLVTFAVL SSVSTIRNQR
YHIHANLSFA ILVAQILLLI SFRFEPGTLP CKVMAVLLHF FFLCAFAWML VEGLHLYSMV
IKVFGSEGSK HFYYYGIGWG SPVVICVVSI TSSLSSYGED GNCWLSLKNG AVWAFVAPAL
FVIMVNIGIL IAVTRIISRI SAENYKVQGD ANSVKLTAKA VAVLLPILGI SWTFGVLAVN
DQSFLFQYMF AVFNSLQGFF IFLFHCLLNS EVRAAFKHKT KVWSLTSSSI RNINVKPFNS
DIMNGNRGGV SPTRMNTWDK STNSANRIDL SAL
//
