ID W5W242_9PSEU Unreviewed; 432 AA.
AC W5W242;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=Aldehyde dehydrogenase {ECO:0000256|PIRNR:PIRNR036492};
GN ORFNames=KALB_1233 {ECO:0000313|EMBL:AHH94606.1};
OS Kutzneria albida DSM 43870.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Kutzneria.
OX NCBI_TaxID=1449976 {ECO:0000313|EMBL:AHH94606.1, ECO:0000313|Proteomes:UP000019225};
RN [1] {ECO:0000313|EMBL:AHH94606.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43870 {ECO:0000313|EMBL:AHH94606.1};
RX PubMed=25301375; DOI=10.1186/1471-2164-15-885;
RA Rebets Y., Tokovenko B., Lushchyk I., Ruckert C., Zaburannyi N.,
RA Bechthold A., Kalinowski J., Luzhetskyy A.;
RT "Complete genome sequence of producer of the glycopeptide antibiotic
RT Aculeximycin Kutzneria albida DSM 43870T, a representative of minor genus
RT of Pseudonocardiaceae.";
RL BMC Genomics 15:885-885(2014).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|PIRNR:PIRNR036492,
CC ECO:0000256|RuleBase:RU003345}.
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DR EMBL; CP007155; AHH94606.1; -; Genomic_DNA.
DR RefSeq; WP_025354836.1; NZ_CP007155.1.
DR AlphaFoldDB; W5W242; -.
DR STRING; 1449976.KALB_1233; -.
DR KEGG; kal:KALB_1233; -.
DR PATRIC; fig|1449976.3.peg.1236; -.
DR eggNOG; COG1012; Bacteria.
DR HOGENOM; CLU_005391_3_1_11; -.
DR OrthoDB; 6882680at2; -.
DR Proteomes; UP000019225; Chromosome.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006081; P:cellular aldehyde metabolic process; IEA:InterPro.
DR CDD; cd07087; ALDH_F3-13-14_CALDH-like; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR012394; Aldehyde_DH_NAD(P).
DR PANTHER; PTHR43570; ALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43570:SF16; ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q; 1.
DR Pfam; PF00171; Aldedh; 1.
DR PIRSF; PIRSF036492; ALDH; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|PIRNR:PIRNR036492};
KW Reference proteome {ECO:0000313|Proteomes:UP000019225}.
FT DOMAIN 3..429
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 211
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1,
FT ECO:0000256|PROSITE-ProRule:PRU10007"
FT ACT_SITE 245
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1"
SQ SEQUENCE 432 AA; 46228 MW; 5BFC5E2318ECB9BB CRC64;
MSTVEEIPAT VARLRETFRT GTTKSLDWRL TQLRGLRAML TEQADEFAAA LHSDLGKSRA
EVDRTELGFV VNEIDHTLAH LAGWLEPQPA AVPDSLPGAS AWTVYDPLGV VLVIAPWNYP
VQLLMAPLAG ALASGNCAVV KPSELAPATS AAIAKHLPGY VQGVAVVEGA IPETTALLEQ
RFDHIFYTGN GVVGRIVMTA AAKHLTPVAL ELGGKSPVFV DGDVDPTEVA KRIVAGKFLN
AGQTCVAPDY VLTDPATARA LEQALPQALR DLFGEDPATS TEYGRIVNHR HFDRLTGLLG
AGRTVVGGQH DRDSKYIAPT VLAGVRAEDP VMAEEIFGPI LPIVEVADLD AAIEFITGRG
KPLALYAFTK SDRTRERLQQ ETSSGALSFE LTVSHLRVSD LPFGGVGESG MGRYHGLYSI
ETFSHRKAVL RG
//
