ID W5XYU6_9CORY Unreviewed; 868 AA.
AC W5XYU6;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000256|ARBA:ARBA00022419, ECO:0000256|HAMAP-Rule:MF_00595};
DE Short=PEPC {ECO:0000256|HAMAP-Rule:MF_00595};
DE Short=PEPCase {ECO:0000256|HAMAP-Rule:MF_00595};
DE EC=4.1.1.31 {ECO:0000256|ARBA:ARBA00012305, ECO:0000256|HAMAP-Rule:MF_00595};
GN Name=ppc {ECO:0000256|HAMAP-Rule:MF_00595};
GN ORFNames=B843_04010 {ECO:0000313|EMBL:AHI22191.1};
OS Corynebacterium vitaeruminis DSM 20294.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=1224164 {ECO:0000313|EMBL:AHI22191.1, ECO:0000313|Proteomes:UP000019222};
RN [1] {ECO:0000313|EMBL:AHI22191.1, ECO:0000313|Proteomes:UP000019222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10234 {ECO:0000313|Proteomes:UP000019222};
RA Ruckert C., Albersmeier A., Kalinowski J.;
RT "The complete genome sequence of Corynebacterium vitaeruminis DSM 20294.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Forms oxaloacetate, a four-carbon dicarboxylic acid source
CC for the tricarboxylic acid cycle. {ECO:0000256|ARBA:ARBA00003670,
CC ECO:0000256|HAMAP-Rule:MF_00595}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=oxaloacetate + phosphate = hydrogencarbonate +
CC phosphoenolpyruvate; Xref=Rhea:RHEA:28370, ChEBI:CHEBI:16452,
CC ChEBI:CHEBI:17544, ChEBI:CHEBI:43474, ChEBI:CHEBI:58702; EC=4.1.1.31;
CC Evidence={ECO:0000256|ARBA:ARBA00001071, ECO:0000256|HAMAP-
CC Rule:MF_00595};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946,
CC ECO:0000256|HAMAP-Rule:MF_00595};
CC -!- SUBUNIT: Homotetramer. {ECO:0000256|HAMAP-Rule:MF_00595}.
CC -!- SIMILARITY: Belongs to the PEPCase type 1 family.
CC {ECO:0000256|ARBA:ARBA00008346, ECO:0000256|HAMAP-Rule:MF_00595}.
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DR EMBL; CP004353; AHI22191.1; -; Genomic_DNA.
DR AlphaFoldDB; W5XYU6; -.
DR STRING; 1224164.B843_04010; -.
DR KEGG; cvt:B843_04010; -.
DR PATRIC; fig|1224164.3.peg.795; -.
DR eggNOG; COG2352; Bacteria.
DR HOGENOM; CLU_006557_2_0_11; -.
DR Proteomes; UP000019222; Chromosome.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR Gene3D; 1.20.1440.90; Phosphoenolpyruvate/pyruvate domain; 1.
DR HAMAP; MF_00595; PEPcase_type1; 1.
DR InterPro; IPR021135; PEP_COase.
DR InterPro; IPR022805; PEP_COase_bac/pln-type.
DR InterPro; IPR018129; PEP_COase_Lys_AS.
DR InterPro; IPR033129; PEPCASE_His_AS.
DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR PANTHER; PTHR30523; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR PANTHER; PTHR30523:SF6; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR Pfam; PF00311; PEPcase; 1.
DR PRINTS; PR00150; PEPCARBXLASE.
DR SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR PROSITE; PS00781; PEPCASE_1; 1.
DR PROSITE; PS00393; PEPCASE_2; 1.
PE 3: Inferred from homology;
KW Carbon dioxide fixation {ECO:0000256|ARBA:ARBA00023300, ECO:0000256|HAMAP-
KW Rule:MF_00595};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|HAMAP-Rule:MF_00595};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842, ECO:0000256|HAMAP-Rule:MF_00595};
KW Pyruvate {ECO:0000313|EMBL:AHI22191.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000019222}.
FT ACT_SITE 114
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00595,
FT ECO:0000256|PROSITE-ProRule:PRU10111"
FT ACT_SITE 532
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00595,
FT ECO:0000256|PROSITE-ProRule:PRU10112"
SQ SEQUENCE 868 AA; 96890 MW; 7F4066BFCBEEB1B0 CRC64;
MLGRVIAQQE GEDVFELVEA TRRMAFDIAH GDAKPTDLMG IFRDLDITKT NLVARSFCYF
ALIANLAEDL ADESVEAPVS LRKTFAKLKD AGVTGADAAA VVRNAKVAPV LTAHPTETRR
RTVFDTQNRI KQLLKESHHG GDMARIEREM YLRITLLWQT ALIRIARPTL EDEVDVGLRY
YKLSLLEQVP ALNRAIRHNM RDTFGMQVPD VPVVRPGSWI GGDHDGNPYV NARTLTYATR
NAAKTVLRFY EEQLGELERE LSLSDRYSSC SKELLALADA AHNDWESRVD EPYRRAIYGI
RNRVRANLHE IGDKKVAQVD AAAYASPEEF KRDLDTIDRS LRQFNDDVIA DDRLARIRSA
VTTFGFHLYT LDLRQNSESF ENVLTEVFAA AGRSDDYRAL GEEEKIALLV EELKTPRPLL
FPDAAPMSEV TEKELGIFRA AAQAVRNFGP QSVSHCIISM TGTVSDILEP MVLLKEVGLR
EVDVVPLFET IDDLKAGAGI LEKLWSVPFY REHLRARGDV QEVMLGYSDS NKDGGYLQAN
WALYDAELAL VELCNAHGIE LRLAHGRGGA VGRGGGPTYD AILAQPKGAV SGSVRITEQG
EVISAKYGAP ETARRHLEAF VSGALVASLT DTEPIADPDR AYAIMRELSD LSGQKYQELV
GDPGFIEYFT QSTPLHEIGD LNLGSRPAAR KQTTAISDLR AIPWVLSWSQ SRTNVPGWFG
VGSAVTRWAG EDASRWEELR ALHRDWPFFR SVMSNMAQVM AKAEISLARL YANLVDDKQI
ADRIYTLIAE EFELTKKVYL EVTGNKDLTA ENQRQARSLK RRYPYLLPLN AIQLELLRRY
RAGDDSFLVS KTIQVTMNGL ATALRNAG
//
