GenomeNet

Database: UniProt
Entry: W5YH69_9ALTE
LinkDB: W5YH69_9ALTE
Original site: W5YH69_9ALTE 
ID   W5YH69_9ALTE            Unreviewed;       487 AA.
AC   W5YH69;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-SEP-2017, entry version 29.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=AU14_06720 {ECO:0000313|EMBL:AHI28421.1};
OS   Marinobacter similis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Alteromonadaceae; Marinobacter.
OX   NCBI_TaxID=1420916 {ECO:0000313|EMBL:AHI28421.1, ECO:0000313|Proteomes:UP000061489};
RN   [1] {ECO:0000313|EMBL:AHI28421.1, ECO:0000313|Proteomes:UP000061489}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A3d10 {ECO:0000313|EMBL:AHI28421.1,
RC   ECO:0000313|Proteomes:UP000061489};
RX   PubMed=24855296;
RA   Ivanova E.P., Ng H.J., Webb H.K., Feng G., Oshima K., Hattori M.,
RA   Ohkuma M., Sergeev A.F., Mikhailov V.V., Crawford R.J., Sawabe T.;
RT   "Draft Genome Sequences of Marinobacter similis A3d10T and
RT   Marinobacter salarius R9SW1T.";
RL   Genome Announc. 2:e00442-14(2014).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP007151; AHI28421.1; -; Genomic_DNA.
DR   EnsemblBacteria; AHI28421; AHI28421; AU14_06720.
DR   KEGG; msx:AU14_06720; -.
DR   KO; K02313; -.
DR   Proteomes; UP000061489; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000061489};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000061489}.
FT   DOMAIN      184    314       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      395    464       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     192    199       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   487 AA;  55231 MW;  653A26ED57171F5A CRC64;
     MPNTMWHQCL EVLRDEFPAQ QFNTWLRPLQ SDLREGQLML FAPNRFVMDW VNEKYLRRIE
     EVLKDLNGGQ APRVNMKVGS APRNSEPVSR SEVSVRSSGA VQEESGSRVT EEEKGVAVSA
     GDNTSVRAKP SNPSYERRPV QVEGDIKHQS FLNEGFTFDT FVEGKSNQLA RAASMQVAEN
     PGGAYNPLFL YGGVGLGKTH LMHAIGNEIV RRKPGAKVAY LRSERFVADM VKALQLNAIN
     EFKRYYRSVD ALLIDDIQFF ARKERSQEEF FHTFNALLEG GQQVIVTCDR FPKEIVDMEE
     RLKSRFGWGL TVMVEPPELE TRVAILMKKA DQANVKLSSE AAFFIAQKIR SNVRELEGAL
     RLVIANAHFT GSEITPPFIR ESLKDLLALH EKQVSIDNIQ RTVAEYYKIK VADLLSKRRT
     RTVTRPRQVA MSLSKELTNH SLPEIGDAFG GRDHTTVLHA CKKIVELQET DPGIREDYQN
     FMRLLTT
//
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