ID W6KJS8_9TRYP Unreviewed; 838 AA.
AC W6KJS8;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Glucosidase II subunit alpha {ECO:0000256|ARBA:ARBA00042895};
GN ORFNames=GSEM1_T00005551001 {ECO:0000313|EMBL:CCW61283.1};
OS Phytomonas sp. EM1.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Phytomonas.
OX NCBI_TaxID=479712 {ECO:0000313|EMBL:CCW61283.1, ECO:0000313|Proteomes:UP000027080};
RN [1] {ECO:0000313|EMBL:CCW61283.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=EM1 {ECO:0000313|EMBL:CCW61283.1};
RA Genoscope - CEA;
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CCW61283.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EM1 {ECO:0000313|EMBL:CCW61283.1};
RX PubMed=24516393; DOI=10.1371/journal.pgen.1004007;
RA Porcel B.M., Denoeud F., Opperdoes F., Noel B., Madoui M.A.,
RA Hammarton T.C., Field M.C., Da Silva C., Couloux A., Poulain J.,
RA Katinka M., Jabbari K., Aury J.M., Campbell D.A., Cintron R., Dickens N.J.,
RA Docampo R., Sturm N.R., Koumandou V.L., Fabre S., Flegontov P., Lukes J.,
RA Michaeli S., Mottram J.C., Szoor B., Zilberstein D., Bringaud F.,
RA Wincker P., Dollet M.;
RT "The Streamlined Genome of Phytomonas spp. Relative to Human Pathogenic
RT Kinetoplastids Reveals a Parasite Tailored for Plants.";
RL PLoS Genet. 10:e1004007-e1004007(2014).
CC -!- PATHWAY: Glycan metabolism; N-glycan metabolism.
CC {ECO:0000256|ARBA:ARBA00004833}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 31 family.
CC {ECO:0000256|ARBA:ARBA00007806, ECO:0000256|RuleBase:RU361185}.
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DR EMBL; HF955064; CCW61283.1; -; Genomic_DNA.
DR AlphaFoldDB; W6KJS8; -.
DR EnsemblProtists; CCW61283; CCW61283; GSEM1_T00005551001.
DR OrthoDB; 5480935at2759; -.
DR Proteomes; UP000027080; Unassembled WGS sequence.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06603; GH31_GANC_GANAB_alpha; 1.
DR CDD; cd14752; GH31_N; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1760; glycosyl hydrolase (family 31); 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 2.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR048395; Glyco_hydro_31_C.
DR InterPro; IPR025887; Glyco_hydro_31_N_dom.
DR InterPro; IPR000322; Glyco_hydro_31_TIM.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR22762; ALPHA-GLUCOSIDASE; 1.
DR PANTHER; PTHR22762:SF54; BCDNA.GH04962; 1.
DR Pfam; PF13802; Gal_mutarotas_2; 1.
DR Pfam; PF01055; Glyco_hydro_31_2nd; 1.
DR Pfam; PF21365; Glyco_hydro_31_3rd; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|RuleBase:RU361185};
KW Hydrolase {ECO:0000256|RuleBase:RU361185};
KW Reference proteome {ECO:0000313|Proteomes:UP000027080};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..838
FT /note="Glucosidase II subunit alpha"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004878001"
FT DOMAIN 44..212
FT /note="Glycoside hydrolase family 31 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13802"
FT DOMAIN 264..598
FT /note="Glycoside hydrolase family 31 TIM barrel"
FT /evidence="ECO:0000259|Pfam:PF01055"
FT DOMAIN 607..694
FT /note="Glycosyl hydrolase family 31 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21365"
SQ SEQUENCE 838 AA; 95268 MW; CE01FBB037ECE92D CRC64;
MSFRGYALLL VLVSFTMALA TDVPLQSTGH ALLVSRIPER KTALYVTPYR DGILRLTIKP
EKEWSFTVPH SVVAEPEAFE TPGLNCTPHD ATCVVEHQNC TMVIRLSQGA SEVIVNYTCV
GLPLVSATVD LQQTPRAVVT STFPSAQTMY GLAEHAADLP LRSGSPYELF NHDAFQYPLN
STNALYGAIP FLMAYSAKAT TGFLFLNAAE LHVVVRERKA PPEEAPPRCE WRAEVGPVDF
FLLPGPTPAQ VQRQHAFLTG PTVFPPYFAL GYHQSRRSYL DFKDALSVDE GFDQHHMPYD
ALWLDVEHTD EGRSFTWDER AFPDAEVLSD ALESKGRRLI TFISPEVRRV ENFTLHEEAE
QGHHAIQDAK GEVFKGEGWV GECSWPDFLN ARTRAWYAGF FQDRESPGKG RSRTHVGVGM
NEPAVRNAPR RTMGKELIHY DDHGHRVEHR SLHNMYGLLS VISAYQGALG AAGEGKAVKT
RPFLLTRSFF AGSQRYAAMW TGDNVARWDH LQSTPAELLS LSISNYPFCG SDVGGFYSEP
EEELFVRWMQ MGIFYPFFRG NANHDTRRRE PWAFSEEAQH HVRYALALRY ALLPYLYTVF
YRAHRHGETV LRPLFFEFPA QEDLWGEQTT FMFGPSLLVS PVVHRKATET TVRLPAREIW
YEYSTGEAIT GRTTYPMPVT LQTIPLFLRG GHIVPLKLRL RRSTYAARGD PFTLYIALNA
KGESRGEFYL DDGTTFHYER GDSLYRRFEF SKYHLRCTKH PEASTNSTFT VSNVVERIVV
MGYNRKPLKI YRVSTTEEGP DPQIAGEPMR FERVGNSIIV HNPRLKIEED WEIRFEND
//
