ID W6L3T3_9TRYP Unreviewed; 612 AA.
AC W6L3T3;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=CNNM transmembrane domain-containing protein {ECO:0000259|PROSITE:PS51846};
GN ORFNames=GSHART1_T00006253001 {ECO:0000313|EMBL:CCW69130.1};
OS Phytomonas sp. Hart1.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Phytomonas.
OX NCBI_TaxID=223615 {ECO:0000313|EMBL:CCW69130.1, ECO:0000313|Proteomes:UP000053358};
RN [1] {ECO:0000313|EMBL:CCW69130.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Hart1 {ECO:0000313|EMBL:CCW69130.1};
RA Genoscope - CEA;
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CCW69130.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hart1 {ECO:0000313|EMBL:CCW69130.1};
RX PubMed=24516393; DOI=10.1371/journal.pgen.1004007;
RA Porcel B.M., Denoeud F., Opperdoes F., Noel B., Madoui M.A.,
RA Hammarton T.C., Field M.C., Da Silva C., Couloux A., Poulain J.,
RA Katinka M., Jabbari K., Aury J.M., Campbell D.A., Cintron R., Dickens N.J.,
RA Docampo R., Sturm N.R., Koumandou V.L., Fabre S., Flegontov P., Lukes J.,
RA Michaeli S., Mottram J.C., Szoor B., Zilberstein D., Bringaud F.,
RA Wincker P., Dollet M.;
RT "The Streamlined Genome of Phytomonas spp. Relative to Human Pathogenic
RT Kinetoplastids Reveals a Parasite Tailored for Plants.";
RL PLoS Genet. 10:e1004007-e1004007(2014).
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DR EMBL; HF955203; CCW69130.1; -; Genomic_DNA.
DR AlphaFoldDB; W6L3T3; -.
DR EnsemblProtists; CCW69130; CCW69130; GSHART1_T00006253001.
DR OrthoDB; 248389at2759; -.
DR Proteomes; UP000053358; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0010960; P:magnesium ion homeostasis; IEA:InterPro.
DR Gene3D; 3.10.580.10; CBS-domain; 2.
DR InterPro; IPR045095; ACDP.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR PANTHER; PTHR12064; METAL TRANSPORTER CNNM; 1.
DR PANTHER; PTHR12064:SF59; UNEXTENDED PROTEIN; 1.
DR Pfam; PF01595; CNNM; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|PROSITE-ProRule:PRU01193, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053358};
KW Transmembrane {ECO:0000256|PROSITE-ProRule:PRU01193,
KW ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|PROSITE-ProRule:PRU01193,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 9..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 39..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 131..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 38..225
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
SQ SEQUENCE 612 AA; 68832 MW; 223649454F9BC296 CRC64;
MQAYLTSKIH YIFCLLLIGI GVVSLEVRAE RLSKDFYMIL PLGVRIPFCV LTIFMAAFYC
GMTLGLMKIN TSTLEIIAES GPEADQRNAR LILPLRRMGH QLLVTLLLGN MLAIVLTSQL
IAAILNSSKV INFMAGTLVI LIFGEIIPMC ICCKGSNALV VGGKLIPALK VSLWIFYPIA
KPLGMLLDLT VKHEPGQIFD RNEFKKLISM QYDKFSEKSG IDKEQVRMML RVLELDGRTA
KTIMTPLSEA FMLEGNMVLN YKLLKCLWNI GKSRLPVYVD ERTNIVGVLY VKDLLNFFLL
DHKVSTTVYN FVMSKARDIV VVDANLRIQE ILAMFKNRIP HLLLVSNCKK GDSQVTTQVV
TPVCAYQEGF STDLKPNQCP PPKNIQNEES NGPFIGILTL EDVIEELIAA EIYDEDEYTD
RSFNPNDAAL TSSPTKMPPN YKLHVNFYSY GLEDIDQPVS GLGKTLLDEQ KWVLADYITR
MYVAFATWSV EDMKKLLDYV GDRIINVTVE ISLCGMVSPD LILYNAGVQT DVFTLLLGGA
AEMKVEKKLS TKVYSFFAFA EEVLLSDQSF VPNYTAVITR SSRVLQISRD DLRMAEEHFK
SDKKKEKHMA SG
//
