ID   W6MKW8_9ASCO            Unreviewed;       571 AA.
AC   W6MKW8;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Choline kinase N-terminal domain-containing protein {ECO:0000259|Pfam:PF04428};
GN   ORFNames=KUCA_T00003023001 {ECO:0000313|EMBL:CDK27046.1};
OS   Kuraishia capsulata CBS 1993.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetales incertae sedis; Kuraishia.
OX   NCBI_TaxID=1382522 {ECO:0000313|EMBL:CDK27046.1};
RN   [1] {ECO:0000313|EMBL:CDK27046.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CBS 1993 {ECO:0000313|EMBL:CDK27046.1};
RA   Genoscope - CEA;
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CDK27046.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CBS 1993 {ECO:0000313|EMBL:CDK27046.1};
RA   Morales L., Noel B., Porcel B., Marcet-Houben M., Hullo M-F., Sacerdot C.,
RA   Tekaia F., Leh-Louis V., Despons L., Khanna V., Aury J-M., Barbe V.,
RA   Couloux A., Labadie K., Pelletier E., Souciet J-L., Boekhout T.,
RA   Gabaldon T., Wincker P., Dujon B.;
RT   "Complete DNA sequence of /Kuraishia capsulata/ illustrates novel genomic
RT   features among budding yeasts (/Saccharomycotina/).";
RL   Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC   -!- PATHWAY: Phospholipid metabolism. {ECO:0000256|ARBA:ARBA00025707}.
CC   -!- SIMILARITY: Belongs to the choline/ethanolamine kinase family.
CC       {ECO:0000256|ARBA:ARBA00038211}.
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DR   EMBL; HG793127; CDK27046.1; -; Genomic_DNA.
DR   AlphaFoldDB; W6MKW8; -.
DR   STRING; 1382522.W6MKW8; -.
DR   HOGENOM; CLU_012712_4_2_1; -.
DR   OrthoDB; 144299at2759; -.
DR   GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
DR   CDD; cd05157; ETNK_euk; 1.
DR   Gene3D; 3.90.1200.10; -; 1.
DR   InterPro; IPR007521; Choline_kin_N.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   PANTHER; PTHR22603; CHOLINE/ETHANOALAMINE KINASE; 1.
DR   PANTHER; PTHR22603:SF93; RE24176P; 1.
DR   Pfam; PF04428; Choline_kin_N; 1.
DR   Pfam; PF01633; Choline_kinase; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE   3: Inferred from homology;
FT   DOMAIN          122..158
FT                   /note="Choline kinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04428"
FT   REGION          55..90
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        75..90
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   571 AA;  65819 MW;  34224CA61A207980 CRC64;
     MKYWGVRLSI LSNRFAHVSH VNAEPQHYRR FRCIPAHETI RLFSTSTPQF LSSLEANHTT
     SMDTPRRSRR SSTKRSNSLP RPTFSRRSSS TSSLHVVDLI DTFKDASVQQ AALSSGQERD
     FVPTVKAHLD QSLPLDYFKQ DIISILQSLR IPRWHKIPIT PSSIAKLELK RINGALTNCI
     FKVTFKNYEP LLLRIYGPNV DSIIDREAEL KTLTRLSANN IGPKLMGCFT NGRFEQYLEN
     STTLDRNHLR DPNISRRIGR RMKELHTGIP LELQERLSGP VCWSTIGKWL DTVEKYADEA
     TLDEQQDVFI LSFKEFKKVI RTYRDWLLES YTEPFQINQN LVFCHNDTQY GNLLFYTPLG
     LEKKGKVTDQ ELVVIDFEYS GPNLPAYDIT NHFCEWMANY HHPTQSYYLD QDAYPSREER
     LNFLDSYVKC KGLSKMKVQH TVPELHDEIL KWRACNSILW ALWAVITNGS LHKNAKILHE
     LFGQETEEKG PNGEIYRITV EEDATFEAGS EGEEVGDDTD DNFDSLGYAL QKMGIVIGDL
     IQFGLLDKDA IDESRLANVK FMDCKLIKDE E
//