ID   W6MT39_9ASCO            Unreviewed;       546 AA.
AC   W6MT39;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Pyridoxamine kinase/Phosphomethylpyrimidine kinase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=KUCA_T00005520001 {ECO:0000313|EMBL:CDK29528.1};
OS   Kuraishia capsulata CBS 1993.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetales incertae sedis; Kuraishia.
OX   NCBI_TaxID=1382522 {ECO:0000313|EMBL:CDK29528.1};
RN   [1] {ECO:0000313|EMBL:CDK29528.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CBS 1993 {ECO:0000313|EMBL:CDK29528.1};
RA   Genoscope - CEA;
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CDK29528.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CBS 1993 {ECO:0000313|EMBL:CDK29528.1};
RA   Morales L., Noel B., Porcel B., Marcet-Houben M., Hullo M-F., Sacerdot C.,
RA   Tekaia F., Leh-Louis V., Despons L., Khanna V., Aury J-M., Barbe V.,
RA   Couloux A., Labadie K., Pelletier E., Souciet J-L., Boekhout T.,
RA   Gabaldon T., Wincker P., Dujon B.;
RT   "Complete DNA sequence of /Kuraishia capsulata/ illustrates novel genomic
RT   features among budding yeasts (/Saccharomycotina/).";
RL   Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; HG793131; CDK29528.1; -; Genomic_DNA.
DR   AlphaFoldDB; W6MT39; -.
DR   STRING; 1382522.W6MT39; -.
DR   HOGENOM; CLU_020520_2_1_1; -.
DR   OrthoDB; 5477821at2759; -.
DR   GO; GO:0008972; F:phosphomethylpyrimidine kinase activity; IEA:InterPro.
DR   GO; GO:0050334; F:thiaminase activity; IEA:InterPro.
DR   GO; GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
DR   CDD; cd01169; HMPP_kinase; 1.
DR   CDD; cd19367; TenA_C_ScTHI20-like; 1.
DR   Gene3D; 3.40.1190.20; -; 1.
DR   Gene3D; 1.20.910.10; Heme oxygenase-like; 1.
DR   InterPro; IPR016084; Haem_Oase-like_multi-hlx.
DR   InterPro; IPR004399; HMP/HMP-P_kinase_dom.
DR   InterPro; IPR013749; PM/HMP-P_kinase-1.
DR   InterPro; IPR029056; Ribokinase-like.
DR   InterPro; IPR004305; Thiaminase-2/PQQC.
DR   InterPro; IPR027574; Thiaminase_II.
DR   NCBIfam; TIGR00097; HMP-P_kinase; 1.
DR   NCBIfam; TIGR04306; salvage_TenA; 1.
DR   PANTHER; PTHR20858:SF17; HYDROXYMETHYLPYRIMIDINE_PHOSPHOMETHYLPYRIMIDINE KINASE THI20-RELATED; 1.
DR   PANTHER; PTHR20858; PHOSPHOMETHYLPYRIMIDINE KINASE; 1.
DR   Pfam; PF08543; Phos_pyr_kin; 1.
DR   Pfam; PF03070; TENA_THI-4; 1.
DR   SUPFAM; SSF48613; Heme oxygenase-like; 1.
DR   SUPFAM; SSF53613; Ribokinase-like; 1.
PE   4: Predicted;
FT   DOMAIN          32..303
FT                   /note="Pyridoxamine kinase/Phosphomethylpyrimidine kinase"
FT                   /evidence="ECO:0000259|Pfam:PF08543"
FT   DOMAIN          337..541
FT                   /note="Thiaminase-2/PQQC"
FT                   /evidence="ECO:0000259|Pfam:PF03070"
SQ   SEQUENCE   546 AA;  59440 MW;  7485187C22BEFABB CRC64;
     MTIDTEIVDL RYLSSSVTNT TLPTVLTVAG SDSSGGAGIE ADIKTITAHG CYALTCITAL
     TAQNTTGVKA IYPTPKESIN GILEANFSDI NVNVVKTGLL TAEAAELLPK YLEKYHKGKP
     LVVDPVIVAA SGDSLAKIED LKISIDNLFR KATIITPNIE ECGAIVSTLR NLSTIAPCNI
     STVEDLKVIA KTIQEGTKCV GVLVKGGHCP FDSEGISVKV SKKSPVSVFD VFYEGHTQNF
     TVFKANYIVT KSSHGTGCTL ASAIAANLGR GLKMKFAVDS ALKYVHSGIL SADSTFGKGS
     IGPLNHIFHV AAPIAIASAS RLPFTEGHFV DYLLGHPIVK PVYERYIHHD FVRRVADGSL
     ERSKFEHYLQ QDYAYLLSYA RVHSLAASVA PELKDIEAEG RILLKVAEEM EHHRQQLENL
     GKDTSNIKMG RACQEYADYL LDLSKSGDWL EINVALAPCL LGYASAAKWG LQLYHGDMDP
     KDEYYKWLAD YSSDWYEESC DLGRQVLESH GASISVTKLS KLVKIFADVT QLEVNFWSAS
     LAYEGK
//