ID   W6MUH9_9ASCO            Unreviewed;      1006 AA.
AC   W6MUH9;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=NFACT RNA-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=KUCA_T00001610001 {ECO:0000313|EMBL:CDK25640.1};
OS   Kuraishia capsulata CBS 1993.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetales incertae sedis; Kuraishia.
OX   NCBI_TaxID=1382522 {ECO:0000313|EMBL:CDK25640.1};
RN   [1] {ECO:0000313|EMBL:CDK25640.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CBS 1993 {ECO:0000313|EMBL:CDK25640.1};
RA   Genoscope - CEA;
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CDK25640.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CBS 1993 {ECO:0000313|EMBL:CDK25640.1};
RA   Morales L., Noel B., Porcel B., Marcet-Houben M., Hullo M-F., Sacerdot C.,
RA   Tekaia F., Leh-Louis V., Despons L., Khanna V., Aury J-M., Barbe V.,
RA   Couloux A., Labadie K., Pelletier E., Souciet J-L., Boekhout T.,
RA   Gabaldon T., Wincker P., Dujon B.;
RT   "Complete DNA sequence of /Kuraishia capsulata/ illustrates novel genomic
RT   features among budding yeasts (/Saccharomycotina/).";
RL   Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the NEMF family.
CC       {ECO:0000256|ARBA:ARBA00008318}.
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DR   EMBL; HG793126; CDK25640.1; -; Genomic_DNA.
DR   AlphaFoldDB; W6MUH9; -.
DR   STRING; 1382522.W6MUH9; -.
DR   HOGENOM; CLU_003612_1_1_1; -.
DR   OrthoDB; 129892at2759; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0072344; P:rescue of stalled ribosome; IEA:UniProt.
DR   Gene3D; 2.30.310.10; ibrinogen binding protein from staphylococcus aureus domain; 1.
DR   InterPro; IPR021846; NFACT-C.
DR   InterPro; IPR008532; NFACT_RNA-bd.
DR   PANTHER; PTHR15239; NUCLEAR EXPORT MEDIATOR FACTOR NEMF; 1.
DR   PANTHER; PTHR15239:SF6; RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF; 1.
DR   Pfam; PF11923; NFACT-C; 1.
DR   Pfam; PF05670; NFACT-R_1; 1.
DR   Pfam; PF05833; NFACT_N; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490}.
FT   DOMAIN          567..677
FT                   /note="NFACT RNA-binding"
FT                   /evidence="ECO:0000259|Pfam:PF05670"
FT   DOMAIN          889..989
FT                   /note="NFACT protein C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF11923"
FT   REGION          438..487
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          772..812
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          825..852
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          336..370
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        444..468
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1006 AA;  113886 MW;  23131014A819C5E3 CRC64;
     MKQRLTSLDI KILVSEAEKS LADCRLQNIY TLANSNRSYL LKFGRPDLKV SLIIDSGFKF
     HTTKFQRPVT QLPSNFVVKL RKHIKSKRLS NVKQVGDDRI VVFEFANGLN YLVLEFFSAG
     NIILLDENLK ILSLQRTVSE HQANDRYAVA ETYQMFTKSL FEENSVEKTG YPEISAGDIK
     SWVEETKKNV DEQKGKVYSI HKQLFLKASY LSSDLIHIHL IKLGIEFGAS CFRLLEDETV
     LQQTTKALHN ASSQLEELVN TPADKFQGYI LSKKNPLYRK AEIEKDESSN LEYIYEEFHP
     FEPIHKVNDN TRISTVTGYN NTIDEFFSTI ETSKHSLKQQ AQQHNAEKRL QQVKDENEAK
     ISKLTEVQQL NFKKAELIVI YSDLIEQCKS AVQSLLDQQM DWKNIEKLIS IEKNRGSEVA
     AMINLPLNLK ENKINVNLPD SLADDDHDES DDSNSSESES ESESDSSDSE TEEKPKPAHS
     KKNSQPTVSV SIDLGLSAYA NSTSYFDAVK VAQEKQTKTE KNANMALKNT EKKIALDMKR
     LTKQQSSQVS GGQTGLVQLR NKFWFEKFYW FISSDGFLCV AGRDTAQVDL LYYKYFNNSN
     DVLVSNDLDN ALKVFIKNPY SNKDIPPTTF IQAGVYSLST TKAWDNKIVT SPWFVKGVDV
     SKKDYDGTIL PSGMLNVARE RTYLPPCQLV MGFGLLWIGD DETTKKYKSA KKTRDSELEL
     KLVDAENGKQ TRIDELKEMV AKIGAPTEED SKIGQELQTH VEDDVETISE SINSLDLKPP
     GPNDQIQSKI RGKKAKLKKI KQKYGDQDEE ERRLRMSVLG TLKQVEKKKS TAEAAESADT
     TAPSRRPPSK KIQEANRLRK LLEELEQDDD IAQEDGEESE VKIGEPYWET ISGLIAAPNK
     SDKILDCIPV FTPWPTLNRY KYKIKVQPGN NKKGKSISDV IDYFSRSNIA QAKSEPEDSA
     EWFDKQNLVA QTNQQNALMA ITPTKLKIVL PGGSDSKSKG KTGKKK
//