ID W6N6I3_CLOTY Unreviewed; 379 AA.
AC W6N6I3;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Butyryl-CoA dehydrogenase {ECO:0000313|EMBL:CDL91795.1};
DE EC=1.3.8.1 {ECO:0000313|EMBL:CDL91795.1};
GN ORFNames=CTDIVETGP_1865 {ECO:0000313|EMBL:CDL91795.1};
OS Clostridium tyrobutyricum DIVETGP.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1408889 {ECO:0000313|EMBL:CDL91795.1, ECO:0000313|Proteomes:UP000019482};
RN [1] {ECO:0000313|EMBL:CDL91795.1, ECO:0000313|Proteomes:UP000019482}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DIVETGP {ECO:0000313|EMBL:CDL91795.1,
RC ECO:0000313|Proteomes:UP000019482};
RA Soggiu A., Piras C., Gaiarsa S., Sassera D., Roncada P., Bendixen E.,
RA Brasca M., Bonizzi L.;
RT "Draft Genome Sequence of Clostridium tyrobutyricum Strain DIVETGP,
RT Isolated from Cow's Milk for Grana Padano Production.";
RL Genome Announc. 3:213-215(2015).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|RuleBase:RU362125};
CC -!- SIMILARITY: Belongs to the acyl-CoA dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009347, ECO:0000256|RuleBase:RU362125}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDL91795.1}.
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DR EMBL; CBXI010000032; CDL91795.1; -; Genomic_DNA.
DR RefSeq; WP_017751936.1; NZ_CBXI010000032.1.
DR AlphaFoldDB; W6N6I3; -.
DR GeneID; 29420641; -.
DR OrthoDB; 9802447at2; -.
DR Proteomes; UP000019482; Unassembled WGS sequence.
DR GO; GO:0004085; F:butyryl-CoA dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:UniProtKB-UniRule.
DR CDD; cd01158; SCAD_SBCAD; 1.
DR Gene3D; 1.10.540.10; Acyl-CoA dehydrogenase/oxidase, N-terminal domain; 1.
DR Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 1.
DR InterPro; IPR006089; Acyl-CoA_DH_CS.
DR InterPro; IPR006091; Acyl-CoA_Oxase/DH_mid-dom.
DR InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009075; AcylCo_DH/oxidase_C.
DR InterPro; IPR013786; AcylCoA_DH/ox_N.
DR InterPro; IPR037069; AcylCoA_DH/ox_N_sf.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR PANTHER; PTHR43884; ACYL-COA DEHYDROGENASE; 1.
DR PANTHER; PTHR43884:SF12; COMPLEX I ASSEMBLY FACTOR ACAD9, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF00441; Acyl-CoA_dh_1; 1.
DR Pfam; PF02770; Acyl-CoA_dh_M; 1.
DR Pfam; PF02771; Acyl-CoA_dh_N; 1.
DR PIRSF; PIRSF016578; HsaA; 1.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
DR PROSITE; PS00073; ACYL_COA_DH_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|RuleBase:RU362125};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU362125};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU362125};
KW Reference proteome {ECO:0000313|Proteomes:UP000019482}.
FT DOMAIN 7..118
FT /note="Acyl-CoA dehydrogenase/oxidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02771"
FT DOMAIN 122..217
FT /note="Acyl-CoA oxidase/dehydrogenase middle"
FT /evidence="ECO:0000259|Pfam:PF02770"
FT DOMAIN 229..374
FT /note="Acyl-CoA dehydrogenase/oxidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00441"
SQ SEQUENCE 379 AA; 41769 MW; 89FB974B1EE2AE07 CRC64;
MDFKQDENHQ QLQEMYRDFA QNEVKPIAKE IDETMRFPKE NVAKMAEMGL LGIPFPEEYG
GAGMDTLSYV QCVEELSKCC ATTGVIVSAH TSLGTTPIYK FGTDAQKEKY VKSLASGEKL
GAFGLTEPVA GTDASMQKTT AVLEGDHYVL NGSKIFITNA GYADVYIIFA MTDKSKGTKG
ISAFIVEKDF PGFSVGSHEL KMGIRASSTC ELFFDNCIVP KENLLGEEGR GFNIAMATLD
GGRVGIAAQA LGIAEGAIDE TVKYVKERIQ FGRPIAKFQN TQFELAKMRA NTEAAKLLVY
QAAYAEDNYK RFTQYAAMAK LFAARNASDV TSRCLQLFGG YGYTSDYPIE RMMRDAKITE
IYEGTSEVQM MVLSGWMLK
//
