ID   W6Q5Y4_PENRF            Unreviewed;       392 AA.
AC   W6Q5Y4;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Pyridoxal phosphate-dependent enzyme, beta subunit {ECO:0000313|EMBL:CDM29659.1};
GN   ORFNames=PROQFM164_S01g003471 {ECO:0000313|EMBL:CDM29659.1};
OS   Penicillium roqueforti (strain FM164).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=1365484 {ECO:0000313|EMBL:CDM29659.1};
RN   [1] {ECO:0000313|EMBL:CDM29659.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FM164 {ECO:0000313|EMBL:CDM29659.1};
RX   PubMed=24407037; DOI=10.1038/ncomms3876;
RA   Cheeseman K., Ropars J., Renault P., Dupont J., Gouzy J., Branca A.,
RA   Abraham A.L., Ceppi M., Conseiller E., Debuchy R., Malagnac F., Goarin A.,
RA   Silar P., Lacoste S., Sallet E., Bensimon A., Giraud T., Brygoo Y.;
RT   "Multiple recent horizontal transfers of a large genomic region in cheese
RT   making fungi.";
RL   Nat. Commun. 5:2876-2876(2014).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the ACC deaminase/D-cysteine desulfhydrase
CC       family. {ECO:0000256|ARBA:ARBA00008639}.
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DR   EMBL; HG792015; CDM29659.1; -; Genomic_DNA.
DR   AlphaFoldDB; W6Q5Y4; -.
DR   OMA; YVFVACG; -.
DR   OrthoDB; 5489296at2759; -.
DR   Gene3D; 3.40.50.1100; -; 2.
DR   InterPro; IPR027278; ACCD_DCysDesulf.
DR   InterPro; IPR001926; TrpB-like_PALP.
DR   InterPro; IPR036052; TrpB-like_PALP_sf.
DR   PANTHER; PTHR43780; 1-AMINOCYCLOPROPANE-1-CARBOXYLATE DEAMINASE-RELATED; 1.
DR   PANTHER; PTHR43780:SF2; 1-AMINOCYCLOPROPANE-1-CARBOXYLATE DEAMINASE-RELATED; 1.
DR   Pfam; PF00291; PALP; 1.
DR   PIRSF; PIRSF006278; ACCD_DCysDesulf; 1.
DR   SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|PIRSR:PIRSR006278-2}.
FT   DOMAIN          34..365
FT                   /note="Tryptophan synthase beta chain-like PALP"
FT                   /evidence="ECO:0000259|Pfam:PF00291"
FT   REGION          80..100
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        111
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006278-1"
FT   MOD_RES         64
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006278-2"
SQ   SEQUENCE   392 AA;  42104 MW;  D89EA245E0AE287C CRC64;
     MSLPIQLPEA FAKIPRYNIL YPTPSPIHPL SSIAPPRLSP HHPLITIHAK REDHSSPLAC
     AGNKYRKLEY IVPDILSQTP LHHSHENNPT PPGPQQGGAA TTLVTEGAIQ SNHTVQVVAL
     ARKLGLKVVI LLHRGTGGGL AAASDKEAFQ HSGNVQINHL LGADVRVCEE GDPLAHDATP
     LLDELRASGQ NPYWIPGGAS LHPLGGLGYA RAAFEIAAQE EEMGLGGSGR FDYIFVACGS
     GSTVGGLVAG FKLLDKIRGL DVSRKVVGIL NSPTKPRAYH EKRVLNFARR AGELIGLDGE
     RDIGIEDVRL DDRFVGTAYG VLDDKSKETL ENMARMEGMV LDPVYTAKVA RGMMHWVDEG
     EVVDSAKPLE QVNILFIHTG GQAALGAYVD VK
//