ID W6QVK6_PENRF Unreviewed; 248 AA.
AC W6QVK6;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 03-MAY-2023, entry version 23.
DE RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 {ECO:0000256|ARBA:ARBA00021776};
GN ORFNames=PROQFM164_S03g000321 {ECO:0000313|EMBL:CDM33597.1};
OS Penicillium roqueforti (strain FM164).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1365484 {ECO:0000313|EMBL:CDM33597.1};
RN [1] {ECO:0000313|EMBL:CDM33597.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FM164 {ECO:0000313|EMBL:CDM33597.1};
RX PubMed=24407037; DOI=10.1038/ncomms3876;
RA Cheeseman K., Ropars J., Renault P., Dupont J., Gouzy J., Branca A.,
RA Abraham A.L., Ceppi M., Conseiller E., Debuchy R., Malagnac F., Goarin A.,
RA Silar P., Lacoste S., Sallet E., Bensimon A., Giraud T., Brygoo Y.;
RT "Multiple recent horizontal transfers of a large genomic region in cheese
RT making fungi.";
RL Nat. Commun. 5:2876-2876(2014).
CC -!- FUNCTION: Essential factor for the assembly of mitochondrial
CC NADH:ubiquinone oxidoreductase complex (complex I).
CC {ECO:0000256|ARBA:ARBA00004069}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
CC Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004273}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; HG792017; CDM33597.1; -; Genomic_DNA.
DR AlphaFoldDB; W6QVK6; -.
DR STRING; 1365484.W6QVK6; -.
DR OMA; IDACHHD; -.
DR OrthoDB; 312326at2759; -.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IEA:InterPro.
DR CDD; cd05125; Mth938_2P1-like; 1.
DR Gene3D; 3.40.1230.10; MTH938-like; 1.
DR InterPro; IPR036748; MTH938-like_sf.
DR InterPro; IPR034095; NDUF3.
DR InterPro; IPR007523; NDUFAF3/AAMDC.
DR PANTHER; PTHR21192:SF2; NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 3; 1.
DR PANTHER; PTHR21192; NUCLEAR PROTEIN E3-3; 1.
DR Pfam; PF04430; DUF498; 1.
DR SUPFAM; SSF64076; MTH938-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Ubiquinone {ECO:0000313|EMBL:CDM33597.1}.
FT REGION 45..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..63
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..85
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 248 AA; 26732 MW; 60C82AB79B940750 CRC64;
MLSPSPQLLR VLRTSLANSR RTSNLTRFCQ IPSATAAPCL VSNSNTGLPS GRRNYSSPIQ
PTRMIPRSHA HKPVSRDRGP ESKEDTQTNF DALNVLGNIP APTTAIDACL DSGFHLNNGV
KLTNGDGLLL VGGEAFAWRP WKAVQGAESD SAAKDAMLNS KGQFELDESV WGLLSLVWPK
PDMLILGLGG SMFPLSPETK RHINSLGIRV DVLDTRNAAA QFNLLATERG VTEIAAAMIP
IGWKARPL
//
