ID W6TZM2_ECHGR Unreviewed; 433 AA.
AC W6TZM2;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063};
DE EC=2.4.1.- {ECO:0000256|RuleBase:RU363063};
GN ORFNames=EGR_10860 {ECO:0000313|EMBL:EUB54280.1};
OS Echinococcus granulosus (Hydatid tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus;
OC Echinococcus granulosus group.
OX NCBI_TaxID=6210 {ECO:0000313|EMBL:EUB54280.1, ECO:0000313|Proteomes:UP000019149};
RN [1] {ECO:0000313|EMBL:EUB54280.1, ECO:0000313|Proteomes:UP000019149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24013640; DOI=10.1038/ng.2757;
RA Zheng H., Zhang W., Zhang L., Zhang Z., Li J., Lu G., Zhu Y., Wang Y.,
RA Huang Y., Liu J., Kang H., Chen J., Wang L., Chen A., Yu S., Gao Z.,
RA Jin L., Gu W., Wang Z., Zhao L., Shi B., Wen H., Lin R., Jones M.K.,
RA Brejova B., Vinar T., Zhao G., McManus D.P., Chen Z., Zhou Y., Wang S.;
RT "The genome of the hydatid tapeworm Echinococcus granulosus.";
RL Nat. Genet. 45:1168-1175(2013).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|RuleBase:RU363063}; Single-pass type II membrane protein
CC {ECO:0000256|RuleBase:RU363063}. Membrane
CC {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 31 family.
CC {ECO:0000256|ARBA:ARBA00008661, ECO:0000256|RuleBase:RU363063}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EUB54280.1}.
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DR EMBL; APAU02000286; EUB54280.1; -; Genomic_DNA.
DR AlphaFoldDB; W6TZM2; -.
DR EnsemblMetazoa; XM_024500109.1; XP_024345476.1; GeneID_36346575.
DR OMA; PQSIPMR; -.
DR OrthoDB; 5403435at2759; -.
DR Proteomes; UP000019149; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016758; F:hexosyltransferase activity; IEA:InterPro.
DR GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
DR InterPro; IPR002659; Glyco_trans_31.
DR PANTHER; PTHR11214:SF3; BETA-1,3-GALACTOSYLTRANSFERASE BRE-5; 1.
DR PANTHER; PTHR11214; BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE; 1.
DR Pfam; PF01762; Galactosyl_T; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|RuleBase:RU363063,
KW ECO:0000313|EMBL:EUB54280.1};
KW Golgi apparatus {ECO:0000256|RuleBase:RU363063};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363063};
KW Reference proteome {ECO:0000313|Proteomes:UP000019149};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968,
KW ECO:0000256|RuleBase:RU363063};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EUB54280.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363063};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363063}.
FT TRANSMEM 24..42
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363063"
SQ SEQUENCE 433 AA; 50151 MW; 1834FE2ED0CCC8EF CRC64;
MPALNSTSAA LEVHPQLPDG RKQALLIIIS CACIIYIFYV HTIHFTTWTT ENWLNKLNFF
NAHCGWNNSI FVSPDGHYQL HLCYSSVYDK SNLLNTTPTI EESKIRINGS SRLLTFEELA
SIPDAEWLPN FDRSVYQLYP QSIPMRETIE LLINDKPISQ PPIFNPWIRF LRVPSRVCSP
LTPARAKIGL TGALTHPTVV IIYKSGVYNF EERRQLRKLY NLSYTDINIH LIFSIGLPRT
SLGNIFQRDG FNEMHEHNDL LVGDYEDSYY NLTLKLFHTF QWAARFCRSY KPVLVYLDDD
YAVNTNKMAN IIRGLTPELR DNLNHGCDVI VNPVFRSTSY FPRWAFSKRE APWPRHTPEY
LGIYSVWGYR HVHDLALAMH FTKPMVIDDT WLGMVQYKLN LPFSRMEGIC SASPTYLQCL
RFVFSSGEDI KAI
//
