ID W6UT89_ECHGR Unreviewed; 693 AA.
AC W6UT89;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Transitional endoplasmic reticulum ATPase {ECO:0000313|EMBL:EUB63911.1};
GN ORFNames=EGR_01039 {ECO:0000313|EMBL:EUB63911.1};
OS Echinococcus granulosus (Hydatid tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus;
OC Echinococcus granulosus group.
OX NCBI_TaxID=6210 {ECO:0000313|EMBL:EUB63911.1, ECO:0000313|Proteomes:UP000019149};
RN [1] {ECO:0000313|EMBL:EUB63911.1, ECO:0000313|Proteomes:UP000019149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24013640; DOI=10.1038/ng.2757;
RA Zheng H., Zhang W., Zhang L., Zhang Z., Li J., Lu G., Zhu Y., Wang Y.,
RA Huang Y., Liu J., Kang H., Chen J., Wang L., Chen A., Yu S., Gao Z.,
RA Jin L., Gu W., Wang Z., Zhao L., Shi B., Wen H., Lin R., Jones M.K.,
RA Brejova B., Vinar T., Zhao G., McManus D.P., Chen Z., Zhou Y., Wang S.;
RT "The genome of the hydatid tapeworm Echinococcus granulosus.";
RL Nat. Genet. 45:1168-1175(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EUB63911.1}.
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DR EMBL; APAU02000004; EUB63911.1; -; Genomic_DNA.
DR AlphaFoldDB; W6UT89; -.
DR STRING; 6210.W6UT89; -.
DR EnsemblMetazoa; XM_024490288.1; XP_024355107.1; GeneID_36336754.
DR OrthoDB; 3584252at2759; -.
DR Proteomes; UP000019149; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043784; DUF5726.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR041588; Integrase_H2C2.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR041373; RT_RNaseH.
DR PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR PANTHER; PTHR37984:SF13; RIBONUCLEASE H; 1.
DR Pfam; PF18996; DUF5726; 1.
DR Pfam; PF17921; Integrase_H2C2; 1.
DR Pfam; PF17917; RT_RNaseH; 1.
DR Pfam; PF00665; rve; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000019149}.
FT DOMAIN 437..533
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 588..619
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 602..617
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 693 AA; 78661 MW; DB5038CD51AD7337 CRC64;
MRKKKEETYD PRPTLVAAPC QRIPLILRAL PRAAVDAGIT HDTDIDQYCN TLAHHVINRE
EQTLTRDFFL CFQKVDEGDE VYAKKLQLLA QRAFSGCPPN MVSNWVTVRF KHGVRPPALG
EKLCNAKTNS LGQLVKLATK KRRPRSSRIR KTEIAWDVIL GADSLRYTKA VLNFAEGTFS
THRATRANTD TSLSKDDVDD ICNALFEAAA IPMSNLDDLY AQLTHISNDE RKELHELLLK
RIPPPLLEEV NRLVEEMLRD DVIKLSKLPS TSPIALVKES DGNLRLCIDY RKVNAVTKRH
YLIARKCVVR TDHQALTWLK AMREIGRSVA LWYEELQQYD FTVQYRRGKG HGNADALSLR
PTPAETGDVM VHTVFLSDPT RHHWRNTQST DSDTALIYDK FLASSHKPTL EEMMSAKGVQ
SPKRLVVPGS LMQTVLQKLQ EQVGHVGEKK MLDASSKRYW WPPLTPDRRN RYILVMVDYF
TKATRAESVK SQNAETVASV FFNRWICQHG VPESVHSDQG PNFKSRFFTE LCKICQILKT
NARHLRTRKA TARRHFEEAM RFARRSVTDN DIRKYEMFAQ TLQQSRGMGG NFRFPAEQGN
AASHANPASN NPYNQGAADE DFNHAAIPDS DLGHCVQSEV IAHVPRSFTK CPPPPRRLSE
EEKALQKWSL TDAKSKKLGT LKPIIKMGDG GSQ
//
