ID   W6ZKH2_COCMI            Unreviewed;       526 AA.
AC   W6ZKH2;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   RecName: Full=Phosphotransferase {ECO:0000256|RuleBase:RU362007};
DE            EC=2.7.1.- {ECO:0000256|RuleBase:RU362007};
GN   ORFNames=COCMIDRAFT_21899 {ECO:0000313|EMBL:EUC50585.1};
OS   Bipolaris oryzae ATCC 44560.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Bipolaris.
OX   NCBI_TaxID=930090 {ECO:0000313|EMBL:EUC50585.1};
RN   [1] {ECO:0000313|EMBL:EUC50585.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 44560 {ECO:0000313|EMBL:EUC50585.1};
RX   PubMed=23357949; DOI=10.1371/journal.pgen.1003233;
RA   Condon B.J., Leng Y., Wu D., Bushley K.E., Ohm R.A., Otillar R., Martin J.,
RA   Schackwitz W., Grimwood J., MohdZainudin N., Xue C., Wang R., Manning V.A.,
RA   Dhillon B., Tu Z.J., Steffenson B.J., Salamov A., Sun H., Lowry S.,
RA   LaButti K., Han J., Copeland A., Lindquist E., Barry K., Schmutz J.,
RA   Baker S.E., Ciuffetti L.M., Grigoriev I.V., Zhong S., Turgeon B.G.;
RT   "Comparative genome structure, secondary metabolite, and effector coding
RT   capacity across Cochliobolus pathogens.";
RL   PLoS Genet. 9:E1003233-E1003233(2013).
CC   -!- SIMILARITY: Belongs to the hexokinase family.
CC       {ECO:0000256|ARBA:ARBA00009225, ECO:0000256|RuleBase:RU362007}.
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DR   EMBL; KI963922; EUC50585.1; -; Genomic_DNA.
DR   RefSeq; XP_007682822.1; XM_007684632.1.
DR   AlphaFoldDB; W6ZKH2; -.
DR   GeneID; 19120134; -.
DR   KEGG; bor:COCMIDRAFT_21899; -.
DR   eggNOG; KOG1369; Eukaryota.
DR   HOGENOM; CLU_014393_4_0_1; -.
DR   OrthoDB; 5481886at2759; -.
DR   UniPathway; UPA00109; UER00180.
DR   Proteomes; UP000054032; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0005536; F:glucose binding; IEA:InterPro.
DR   GO; GO:0004396; F:hexokinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0001678; P:intracellular glucose homeostasis; IEA:InterPro.
DR   Gene3D; 3.30.420.40; -; 1.
DR   Gene3D; 3.40.367.20; -; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR001312; Hexokinase.
DR   InterPro; IPR022673; Hexokinase_C.
DR   InterPro; IPR022672; Hexokinase_N.
DR   PANTHER; PTHR19443; HEXOKINASE; 1.
DR   PANTHER; PTHR19443:SF29; PHOSPHOTRANSFERASE; 1.
DR   Pfam; PF00349; Hexokinase_1; 1.
DR   Pfam; PF03727; Hexokinase_2; 1.
DR   PRINTS; PR00475; HEXOKINASE.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   PROSITE; PS51748; HEXOKINASE_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU362007};
KW   Glycolysis {ECO:0000256|RuleBase:RU362007};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|RuleBase:RU362007};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU362007};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU362007}.
FT   DOMAIN          17..238
FT                   /note="Hexokinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00349"
FT   DOMAIN          250..521
FT                   /note="Hexokinase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03727"
SQ   SEQUENCE   526 AA;  56492 MW;  790B2D38D1D6C4B8 CRC64;
     MASTDAAVPI DAFTSLINTT TLLDLARRFS ATYSHLARTS TEHFLATPVT ALPTGKEKGK
     FLSIDVGGTN LRVGFVELIG EPDASAGSER SRSSTIGDNV FAQINRSHDK NWPIGDHLKM
     DQAEDLFAWI GDCIAEVVKG ALDEQESSDS QVSSPLGDEI LLGITFSFPM AQTRLSEATL
     LPMGKGFAIT SDLNLGKMLL AGYARHCDAS QQNKPPLPRI RVAAITNDTV ATFASLAYAV
     KASPNSRVSM GLIVGTGTNA TVPMKLDHLH PAKKSALANP DAVETVVINT EWTIRGTDKP
     LIDLNIKTPW DMTLDANSDA PGFQPFEYMT SGRYLGEIVR LIFIDVVSKD SSVQIPPSLQ
     TKNALPTRFL SEVIARKGGR IVQQELENRY PDASPSDDPF WTVDRVEMIR DIAEAVQQRS
     SALVAAACVG LLNCVGEVSL DGAKAPSNGT QHSSKGKREI EELVIAYAGG TISQYPKWLQ
     TCQQWIDILV EEGSAANSSK QVTLKEAKDG GIIGAGVLAA MTDDMA
//