ID   W7A688_9APIC            Unreviewed;       889 AA.
AC   W7A688;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   22-FEB-2023, entry version 30.
DE   SubName: Full=tRNA-specific 2-thiouridylase {ECO:0000313|EMBL:EUD64599.1};
GN   ORFNames=C922_05014 {ECO:0000313|EMBL:EUD64599.1};
OS   Plasmodium inui San Antonio 1.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX   NCBI_TaxID=1237626 {ECO:0000313|EMBL:EUD64599.1, ECO:0000313|Proteomes:UP000030640};
RN   [1] {ECO:0000313|EMBL:EUD64599.1, ECO:0000313|Proteomes:UP000030640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=San Antonio 1 {ECO:0000313|EMBL:EUD64599.1,
RC   ECO:0000313|Proteomes:UP000030640};
RG   The Broad Institute Genome Sequencing Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA   Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Plasmodium inui San Antonio 1.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KI965493; EUD64599.1; -; Genomic_DNA.
DR   RefSeq; XP_008818809.1; XM_008820587.1.
DR   AlphaFoldDB; W7A688; -.
DR   EnsemblProtists; EUD64599; EUD64599; C922_05014.
DR   GeneID; 20040288; -.
DR   VEuPathDB; PlasmoDB:C922_05014; -.
DR   OrthoDB; 231303at2759; -.
DR   Proteomes; UP000030640; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   PANTHER; PTHR43052; -; 1.
DR   PANTHER; PTHR43052:SF1; TRNA-5-TAURINOMETHYLURIDINE 2-SULFURTRANSFERASE; 1.
DR   Pfam; PF03054; tRNA_Me_trans; 1.
DR   SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE   4: Predicted;
FT   REGION          536..580
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        543..578
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   889 AA;  102140 MW;  C4EFFC73FDDDFE66 CRC64;
     MNRKDAHRWR IPECYIVKGG LRRRLSKGGP SPSVNKLNRC AVTPLSGEAC GNDYTKPNKH
     YEAHIRNVCE ELQQMNDRED KMRHLMRENT NVCTVNLSEP VDRRSFTLRH KSKSGSAGRD
     YFINEVSEGV LYRYVERCNS NLYLAVDVVD AGGEEGCEVD LICPPSEQSL RRSDHSCDTS
     HWQSILRRKK FTITVDGFSD NIVLFSFLRV LLKGLKRLDL QCFLNMGFEG VVNQLSHLYT
     IHVNWEQIAG HVMSQVERFL GRLCREVENQ GVSKRLLGRP PVQRNMHMYR YPRVAHMLSG
     GVDSLMALRL LERKKFHVHN FFLNFAHQDC SKSDLKYVKK ICAKRKNLFI VNINEEYTEE
     VLIPMLRSYS EGNIPNADIL CNEKVKYNLL IRTMRKLCRE RGDGWDYSYV STGHYAMIST
     NDERNANRLF SRDFPYVGDD TDGEVKGRTP RKRYRLIVGR DEKKDQTFFL SSFSEKQLSR
     FLFPLCLHRK SDVKRIMEGR AAGKYNRKET RGLCLYGRVD MNSLLGLYLG GGSMTRVGSE
     GESEGGSIER ERGPVEREKG PLERGRNPTE KERSSAEESL PIKAASGAAR ALQWDTNQLR
     SPEFRAFQEK HLPSFDLRFK NYIINVEDGT VLDTNEGIHL YAIGQKKHIT NHLHQVYNAK
     GRGRSCQKNF ISSCQWTVVY KKMLRCGNGD VKESFKENFI YVSRDYGSAL FRHLRGRCKL
     GAFRWVASVS PSYLRGGASK KDAAERDEAD RTLIMPATSR KLAGQFICVR VRNSEQIKEA
     KIALDDLGET AYLTLKQKDI GLSPGQIITL YLPFIVKGNG KAKYVYSLRR GKKDSRIFFH
     CLGSARIINQ YLNRGLYRRL MEIHRRNNLP LWGRDKHCGL VNSEAALQS
//