ID W7ACP3_9APIC Unreviewed; 1846 AA.
AC W7ACP3;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Gamma-tubulin complex component {ECO:0008006|Google:ProtNLM};
GN ORFNames=C922_00353 {ECO:0000313|EMBL:EUD69490.1};
OS Plasmodium inui San Antonio 1.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=1237626 {ECO:0000313|EMBL:EUD69490.1, ECO:0000313|Proteomes:UP000030640};
RN [1] {ECO:0000313|EMBL:EUD69490.1, ECO:0000313|Proteomes:UP000030640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=San Antonio 1 {ECO:0000313|EMBL:EUD69490.1,
RC ECO:0000313|Proteomes:UP000030640};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium inui San Antonio 1.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TUBGCP family.
CC {ECO:0000256|ARBA:ARBA00010337}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KI965460; EUD69490.1; -; Genomic_DNA.
DR RefSeq; XP_008814192.1; XM_008815970.1.
DR EnsemblProtists; EUD69490; EUD69490; C922_00353.
DR GeneID; 20035627; -.
DR VEuPathDB; PlasmoDB:C922_00353; -.
DR OrthoDB; 226505at2759; -.
DR Proteomes; UP000030640; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005815; C:microtubule organizing center; IEA:InterPro.
DR GO; GO:0000922; C:spindle pole; IEA:InterPro.
DR GO; GO:0043015; F:gamma-tubulin binding; IEA:InterPro.
DR GO; GO:0007020; P:microtubule nucleation; IEA:InterPro.
DR Gene3D; 1.20.120.1900; Gamma-tubulin complex, C-terminal domain; 1.
DR InterPro; IPR007259; GCP.
DR InterPro; IPR040457; GCP_C.
DR InterPro; IPR042241; GCP_C_sf.
DR InterPro; IPR041470; GCP_N.
DR PANTHER; PTHR19302; GAMMA TUBULIN COMPLEX PROTEIN; 1.
DR PANTHER; PTHR19302:SF14; GAMMA-TUBULIN COMPLEX COMPONENT 3; 1.
DR Pfam; PF04130; GCP_C_terminal; 1.
DR Pfam; PF17681; GCP_N_terminal; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701}.
FT DOMAIN 176..392
FT /note="Gamma tubulin complex component protein N-terminal"
FT /evidence="ECO:0000259|Pfam:PF17681"
FT DOMAIN 1147..1413
FT /note="Gamma tubulin complex component C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04130"
FT REGION 97..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1338..1362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1431..1481
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 97..117
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 118..144
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1431..1468
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1846 AA; 212786 MW; 869F7E8D59EDCFC8 CRC64;
MIHEIILSLI GQTGDIIILA DKRRNKTKKE SNLNIDEYCF EVNNNIHIFL NSEIKIINDI
VQLGYYFYVM NIFCLLVKKN TIYKNLTHVH KFNKLSEERK GRKGKGGTRE RLQRDEDISS
TASSSSNSSS YESSSDNESE DSNHLNNSNQ EERYEKKKQI DNYFGVILKN IKSLNSVSPY
GYYANGISNE ISKFMRRYMK KISEIEEYIN NNSNTPLTQI LTMLEKNREE IIIIINIIKN
YLEFQKKEEE NVLEGESRNK TKEIMDYLYE NCVSGNSRIK GIYHRYFKNL GKILLHQIFS
WILYGQLLDP YYEFFIQKRQ FIYSDDKKIF LSPEELYENL TLTNVQSLNF EWNYLFFQSV
SNLPDCCLDK VIGRKILFIG KSIRILIRSN KWNTSDIVKL FAITKILSKA FDEASPTAGY
EEVANLEQVT TPMKPHKGVG SEQGLNRTSG VGTTMGEPTS NTNHYLHSLN ISSSDTSYNC
SDESSSAGNK DETINLYCKE IFDITIEKIR SIIAYKLWKY VVKDINLIKI FDLFRDIYLL
NNGDFYDYFL EKSWSLMHTP PNSKNEILLK VLAWKNSSLS VEEYCKAKYE NKKDKLVLEK
YEDDVLFGED NGDLNESTFF SSTNGYHFDS DNSENIISKY FYPRISYKKF SYDSFEREKY
DNLVLGGMCY MYDKKIILND FYKGIQTLSK KKYYDYDNVF SVCVNNYRQQ ILRGFKHGFD
FSVNFNNFFD NKFADIGSNN GTNVKSGAVS GNAKQDFADE NFLLGCCFAL VIHSMKNPLL
YKTDVLHSSL GYWGSLGDCL SVEIKVKFYQ KENGAQEDAS SDQQTANPVQ YGDNHNNVIL
GDVEVEVSLY IGGKGISSFV HNSNSYTVDY ARESILNNKL WADNVNHEKK RLYEDMENDE
GYLRKRNANS ADAANQDDLM SEDVEGNYDE AIKKPVLKIQ SNKQTFYNIN KNTLTKFRVR
INCLKHSFSV YIQKLDEYNL QLNNPKNKIK PIIHIRALDM TQAFTLDIGN GYIGFYTCPI
LFKHKLLEKK NKLNQWFKQF YSETLNVRSP IYKRNFFNMG DEKNKEAIQN EMRNINKMIL
YRNENSQKKG KSAPEMISCA RDKMKNALLF SSYDCSVEIY KWFHQSYKSP IEIPEIDIDN
ETLIFYDKQI NKNIQIHSGL NLWNNIEIYF KLTWPIALII NTSTIYTYNS IFQFLFLLGR
IYYNLKILCY HNRYLYKYLN FKKGGLLFSH LFSIRYKMQF FFFHLIKYLQ EDIINYEYKL
MITQIHKSKD FEYTKSIHDL YLSQVATKCF LRVQDITNPL LELIDTSFKF CYFFQCLIEN
ELFTDILNYE LVDEQEKNKT KKGDMAEEQD EQHNDNHEEK DNDLNQVIEK LLQYNDTFNE
KLVSVMNEMV NISSNSNHAY LVHFLTTLDF NNYVRKIKDS VANAKSIGAS LKDSGTRNEQ
TQQGPPIEGS KSDLGNAVGS SPVRSSVGDN RRDSNKRDDH KMEYIGIENV NSSDNYHAEG
KENYANRLIS GLSHHIRGVD YTNDANQLGS NKDFLKKRVI NKFSNLLHSD VEEKWGMQRS
GINQYSRIGM SESVDRSVLK SVLNGAPSLS RYGNADSYYG IGNDANYGNA GSYNRGGIAN
NNYNALIDKY SNILNSYMNN SGGSNSVYQA SQNYINNSHV NSYSASLDVA KLRHIGDASH
MVDAGNADNA GDAISMGAVP GASNFSVHSL DAGINSNNNV PGYENSLASN MSNLLRKLDV
NGKSNFSQNL LSANHDAHGN APIDLNSLHD LNIKQNFNVQ NLLDNYNYNG FSENGSFTSH
NLDKVSNENN LTSQMYNLSS ASNYGNLSLN VYRNENNNIS EADREK
//
