ID W7IS95_9PSEU Unreviewed; 730 AA.
AC W7IS95;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Phospholipase A2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=UO65_0894 {ECO:0000313|EMBL:EWC63805.1};
OS Actinokineospora spheciospongiae.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinokineospora.
OX NCBI_TaxID=909613 {ECO:0000313|EMBL:EWC63805.1, ECO:0000313|Proteomes:UP000019277};
RN [1] {ECO:0000313|EMBL:EWC63805.1, ECO:0000313|Proteomes:UP000019277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EG49 {ECO:0000313|EMBL:EWC63805.1,
RC ECO:0000313|Proteomes:UP000019277};
RX PubMed=24604655;
RA Harjes J., Ryu T., Abdelmohsen U.R., Moitinho-Silva L., Horn H., Ravasi T.,
RA Hentschel U.;
RT "Draft Genome Sequence of the Antitrypanosomally Active Sponge-Associated
RT Bacterium Actinokineospora sp. Strain EG49.";
RL Genome Announc. 2:e00160-14(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWC63805.1}.
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DR EMBL; AYXG01000033; EWC63805.1; -; Genomic_DNA.
DR RefSeq; WP_052020684.1; NZ_AYXG01000033.1.
DR AlphaFoldDB; W7IS95; -.
DR STRING; 909613.UO65_0894; -.
DR PATRIC; fig|909613.9.peg.910; -.
DR eggNOG; COG1835; Bacteria.
DR OrthoDB; 3389925at2; -.
DR Proteomes; UP000019277; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004623; F:phospholipase A2 activity; IEA:InterPro.
DR GO; GO:0050482; P:arachidonic acid secretion; IEA:InterPro.
DR GO; GO:0006644; P:phospholipid metabolic process; IEA:InterPro.
DR Gene3D; 1.20.90.10; Phospholipase A2 domain; 1.
DR InterPro; IPR036444; PLipase_A2_dom_sf.
DR InterPro; IPR015141; PLipase_A2_prok/fun.
DR Pfam; PF09056; Phospholip_A2_3; 1.
DR SUPFAM; SSF48619; Phospholipase A2, PLA2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019277};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 245..271
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..342
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 386..404
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 410..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 441..462
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 482..502
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 523..544
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 556..575
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 596..619
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 625..648
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 704..730
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 730 AA; 75829 MW; 8E266531BC600BA8 CRC64;
MSGGAPPERD PAGRRVRSRL GWLVLVVLAA AGFAVVASRS PAPAEHPPTG DVARAATAVD
ALLHPSSGRD PLAELPADFT AEVGVVPDRL PAPDGTTRSV HVDGGCSTPW GDDDTRWDFS
VGCKAHDLGY DLLRYAAAKG QPLPPDARRD LDARLSADMH RQCELNPRGS GGTCRVVASL
YSAGLVANSW HQRWGPPVSE PMGGWAMAAL VVVVLLAVRV PAFARRRVPR EDAHRLTEAE
GDRAAYLGLV RLLSLGGIVL AESVLAFGPL LSVPVADLWP VTWLLQLVPL FFFAGGNSNL
LAWRAARAAG TGYGGYLARR VSWLIRPVLA FVTAWLVVPL SLDLLDAPDA VVAAFGRLVA
QPLWLLGLYL LVVGAAPVAQ WAHERAPLLT PAALAAGVVG LAVAGSGSVA AHLGGIVLAL
FFGQLSFLYA DGTLWRPRRR VPAVVAAGAL LGLVLLTTVF GSSPGLIAEP AETASFVPSA
PAVLLLGLAQ VCLVVAPGPA GVRAVARGAA VRAVRFARSA PMTVYLVYLC ALLLLAGVVG
ALRWTRAAGW VPSPRTLAAI GLLAVPTALA FLLFERHRHT PEPVAEHPRP GSRWEVVAAT
LGTAYGALGI VGFAVTGLTG TGHGAVVLGM PMDPMAGVIH LLLGWYLLHS VRVGTGATPW
PWLLAAVACV PPMVTTVSDT GDVVHSITIG VALLAAVATA WPRRGPGRPG SSEPVSRRPA
RVNGGSGVPG
//
