ID W7JLN9_PLAFO Unreviewed; 816 AA.
AC W7JLN9;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 22-FEB-2023, entry version 35.
DE RecName: Full=Peptidase A1 domain-containing protein {ECO:0000259|Pfam:PF00026};
GN ORFNames=PFNF54_05470 {ECO:0000313|EMBL:EWC85803.1};
OS Plasmodium falciparum (isolate NF54).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=5843 {ECO:0000313|EMBL:EWC85803.1, ECO:0000313|Proteomes:UP000030673};
RN [1] {ECO:0000313|EMBL:EWC85803.1, ECO:0000313|Proteomes:UP000030673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NF54 {ECO:0000313|EMBL:EWC85803.1,
RC ECO:0000313|Proteomes:UP000030673};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum NF54.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KE123882; EWC85803.1; -; Genomic_DNA.
DR AlphaFoldDB; W7JLN9; -.
DR EnsemblProtists; EWC85803; EWC85803; PFNF54_05470.
DR OMA; TKTMTII; -.
DR Proteomes; UP000030673; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR InterPro; IPR033121; PEPTIDASE_A1.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR Pfam; PF00026; Asp; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030673};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 783..804
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 485..726
FT /note="Peptidase A1"
FT /evidence="ECO:0000259|Pfam:PF00026"
FT REGION 145..178
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..178
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 816 AA; 95387 MW; FA84E83ECD337E9F CRC64;
MDVQKKKCKT YYLIAILIWF ILISVVLSRG EIINKHVKKK EGNYKNYEDL DSDINKKNNY
YDDKHKNKRL LNGHKNHPEE NKNYTYDDKT KFTKFNKHKN EELFTPNPPL NYEKQTLSNH
QNINFDSTVE EGNKDLNNSG NIISQELEKK LSTDNHKEEG ERKKEETNKK HDIDTNNMDD
NEEKNIYEYF NKKTKDNFDG LILNIYFTPN NNLYTKVKVG DQVLKLSLNS RLEGVYVFMK
DSPACYLEDD DKRTCYNPLM SRNSTWCNND LMCLPAILTK PYECYEDSSL NLENKVQYPN
VYYDSLKFNE THIEGSDDLE FIDLVGVQTK YIRNKKKKMD VNKMMSNENK SMDPKHVENN
LQNNNILKRD NIIIKPRVKL SENSNLLFQG VDIKLVVDMT FYNDWNLFKD TDGMFGLAGK
ELSCRNISAW NNILENNNSI FALDINLPND AIKTYPTPPV NSVGTLYYEY DLKKNGDNKK
SSDQNINNVK DNMIDNKNVD VGVQNINEFE TSSSVIHIGN YSKEYGNIIW SEPRERGGIF
SDSFIQFTIY NLEVCNKNIF GKYSSNWQAI IDLSSQCLVL PKMFWLSLME YLPVNKDDDR
YYEENSLPRM CSVDHRNRPL PTLKFFLSDN DIVSDNNIYS SPESENKGKN EKKNEKQAIY
IPLDNLIIND KKNNQNYLCV IPDVHDGRST ENSARTTKPL IKFGTYVLNN FYVVVDQENY
KVGFANKKSF HTSNEKCTQR TQCIGDQYYE PALNICVDPD CSIWYFYTLN DQTKKCESLS
SRFYVFIIII LTLLILDIQS YYFYRKSVHV AKTSSR
//
