ID W7KNG8_PLAFO Unreviewed; 603 AA.
AC W7KNG8;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Tr-type G domain-containing protein {ECO:0000259|PROSITE:PS51722};
GN ORFNames=PFNF54_00096 {ECO:0000313|EMBL:EWC91132.1};
OS Plasmodium falciparum (isolate NF54).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=5843 {ECO:0000313|EMBL:EWC91132.1, ECO:0000313|Proteomes:UP000030673};
RN [1] {ECO:0000313|EMBL:EWC91132.1, ECO:0000313|Proteomes:UP000030673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NF54 {ECO:0000313|EMBL:EWC91132.1,
RC ECO:0000313|Proteomes:UP000030673};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum NF54.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: This protein promotes the GTP-dependent binding of aminoacyl-
CC tRNA to the A-site of ribosomes during protein biosynthesis.
CC {ECO:0000256|ARBA:ARBA00003982}.
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DR EMBL; KE123717; EWC91132.1; -; Genomic_DNA.
DR AlphaFoldDB; W7KNG8; -.
DR EnsemblProtists; EWC91132; EWC91132; PFNF54_00096.
DR OMA; IPFMNKT; -.
DR Proteomes; UP000030673; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR PANTHER; PTHR43721:SF11; SELENOCYSTEINE-SPECIFIC ELONGATION FACTOR; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000030673}.
FT DOMAIN 1..321
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 243..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 521..580
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 540..580
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 603 AA; 70054 MW; E88C3CFC71E00301 CRC64;
MININVGVLG HVDSGKTSLC KCLSQVLSTC ALDKHKESKE RGITIDLGFS SFYIKKKKKK
KYDVNQKREI QTNLLNDQTT DQKESFLYCK REEKNDLHNI QYDKTNIEYN EEQNCYDYTN
DKHHSNNIYF YDEEIIQICL VDCPGHHSLL KSIIMGSEIT DIIILVIDIN KGIQKQTIEC
LVLCKIINCD IIIVLNKIDL IPLHLREKKI NLMKKKIQEA FYKFKSLQSL NYHIVSISAN
VKGKDNKDVE GDPPNLLSHD KKGKDPPNLL NDDKKDPSIL LNDHMNEWSQ NKSSSDIPFM
NKTINIKEII NVLTNIIKIP EREISTYEDF YFLYDHSFNI KGKGTIFTGT VIKGKIKINC
NVTILPLNET GKIKEIQSFK KNVHEGKKGS RLSLLILNNN IKNIKKNERG VIIYENSNIS
YFSMFICKVK QVEFYKKDLN NLEHFICIIG FSSTECYGYF FKKIKNKYET NESKKINYKE
NSQGHDVFPT LLEDTLNVDK RFDRKGNYLL INKLCYDDTQ KENNNNNKKN KKNNNNKKNK
KNGNKNEHSD DIIKNEHGED INKNEHSDDN NKNEHGDDNN KNEHDASCNT FFLFFCLNIS
AFI
//
