ID W7KVY7_9CREN Unreviewed; 352 AA.
AC W7KVY7;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=X-Pro dipeptidase {ECO:0000313|EMBL:EWG07436.1};
DE SubName: Full=X-pro aminopeptidase {ECO:0000313|EMBL:KJR79046.1};
GN ORFNames=ASUL_05571 {ECO:0000313|EMBL:EWG07436.1}, TQ35_04055
GN {ECO:0000313|EMBL:KJR79046.1};
OS Candidatus Aramenus sulfurataquae.
OC Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Aramenus.
OX NCBI_TaxID=1326980 {ECO:0000313|EMBL:EWG07436.1, ECO:0000313|Proteomes:UP000054284};
RN [1] {ECO:0000313|EMBL:EWG07436.1, ECO:0000313|Proteomes:UP000054284}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AZ1-illumnia {ECO:0000313|EMBL:EWG07436.1};
RX PubMed=24604657;
RA Servin-Garciduenas L.E., Martinez-Romero E.;
RT "Draft Genome Sequence of the Sulfolobales Archaeon AZ1, Obtained through
RT Metagenomic Analysis of a Mexican Hot Spring.";
RL Genome Announc. 2:e00164-14(2014).
RN [2] {ECO:0000313|EMBL:KJR79046.1, ECO:0000313|Proteomes:UP000053480}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AZ1-454 {ECO:0000313|EMBL:KJR79046.1};
RA Servin-Garciduenas L.E., Martinez-Romero E.;
RT "Metagenome Sequencing of an Archaeal-Dominated Microbial Community from a
RT Hot Spring at the Los Azufres Geothermal Field, Mexico.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|RuleBase:RU000590}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWG07436.1}.
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DR EMBL; ASRH01000004; EWG07436.1; -; Genomic_DNA.
DR EMBL; JZWS01000026; KJR79046.1; -; Genomic_DNA.
DR AlphaFoldDB; W7KVY7; -.
DR PATRIC; fig|1326980.6.peg.1107; -.
DR Proteomes; UP000053480; Unassembled WGS sequence.
DR Proteomes; UP000054284; Unassembled WGS sequence.
DR GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01092; APP-like; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 1.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR001131; Peptidase_M24B_aminopep-P_CS.
DR PANTHER; PTHR46112; AMINOPEPTIDASE; 1.
DR PANTHER; PTHR46112:SF9; XAA-PRO AMINOPEPTIDASE; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
DR PROSITE; PS00491; PROLINE_PEPTIDASE; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000313|EMBL:KJR79046.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU000590}; Protease {ECO:0000313|EMBL:KJR79046.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054284}.
FT DOMAIN 4..128
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 137..335
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
SQ SEQUENCE 352 AA; 40009 MW; 20C340CAD522889A CRC64;
MRTRIKKLQS VLEKENIDFT ILGPTSNMFY FTGFREEQME RPLFFIVSKR NSFFFAPKIY
EEQLQKMDFD VVVYNDGEDP YTKLDIPKGA SLAVDDQLWS VFLVNLINKF SPSNLLPASA
LISPLRMVKD EEEIRTLKEG LKIAETAFTR FLDEVSEGDS ECRLARKLDE EFVNLGGEGA
SFGTIVTSGS NTSMPHLRCT EKKIRRGDVI LVDFGVKYKG YSTDTTRVVS LGNPGEEVKK
IYEIVRGAQE EAENSLEGMT GDEIDSLARN YMRKYSVDQF FIHRTGHGIG IDVHEEPYIS
QGYNKKITRN MVFTVEPGVY IQGKFGIRLE DMVVMDGKPK VLNSLSKEIF AL
//
