ID W7PIG9_9ENTR Unreviewed; 794 AA.
AC W7PIG9;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
DE AltName: Full=Beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00030512};
DE AltName: Full=N-acetyl-beta-glucosaminidase {ECO:0000256|ARBA:ARBA00033000};
GN Name=chb {ECO:0000313|EMBL:EWG74926.1};
GN ORFNames=P349_02291 {ECO:0000313|EMBL:EWG74926.1};
OS Enterobacter sp. DC4.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Enterobacter.
OX NCBI_TaxID=1395580 {ECO:0000313|EMBL:EWG74926.1, ECO:0000313|Proteomes:UP000019283};
RN [1] {ECO:0000313|EMBL:EWG74926.1, ECO:0000313|Proteomes:UP000019283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DC4 {ECO:0000313|EMBL:EWG74926.1};
RX PubMed=24625871;
RA Gan H.M., Triassi A.J., Wheatley M.S., Savka M.A., Hudson A.O.;
RT "High-Quality Draft Whole-Genome Sequences of Three Strains of Enterobacter
RT Isolated from Jamaican Dioscorea cayenensis (Yellow Yam).";
RL Genome Announc. 2:e00170-14(2014).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWG74926.1}.
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DR EMBL; AZUB01000003; EWG74926.1; -; Genomic_DNA.
DR RefSeq; WP_032651470.1; NZ_AZUB01000003.1.
DR AlphaFoldDB; W7PIG9; -.
DR PATRIC; fig|1395580.4.peg.2277; -.
DR Proteomes; UP000019283; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 2.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 2.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000313|EMBL:EWG74926.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EWG74926.1};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..794
FT /note="beta-N-acetylhexosaminidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004897467"
FT DOMAIN 26..155
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 159..416
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT DOMAIN 544..584
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 315
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 794 AA; 88456 MW; FD086A0A3623DFBB CRC64;
MLRYSLLTAG LMLGASAFAA PAGDLPLMPW PAKVERPTTQ GALVLNDKIS VSVSGDDLGD
AVNRLRQRIA LQTGWTLQPQ AEKPDKPTIR IAIAKKVKPQ PLPDSDETYK LTVDANGVTI
SANTRFGALR AMETLLQLMQ NGAENTSLPW VAIEDSPRFP WRGLLLDSAR HFIPLPDIKR
QIDGMAAAKL NVLHWHLTDD QGWRFSSKRY PKLTQLASDG LFYTPEQMRE VVRYAAERGI
RVVPEIDMPG HASAIAVAYP ELMSAPGPYA MERHWGVLKP VLDPTKDATY TFADAMVSEL
AAIFPDPYLH IGGDEVDDSQ WKANPAIQQF MRDNRLADSH ALQAYFNRKL ETILEKHHRQ
MVGWDEIYHP DLPKSILIQS WQGQDALGQV AQSGYKGILS TGFYLDQPQS TAYHYRNEIV
PQGLNGVDVI ADTDSAQSWA FSMPRLKGKP VEGSFTLVKG DAGWRGFIDF AGKSRRAVQN
IEWRDDSLVT FTVDTWMGET RPVVTVDNDK LSGYFLVGNT RYPISGTRLD DVPKGVPPVV
PDVANQGNLL GGEAALWAEN VVAPVLDIRL WPRTFAVAER LWSAQDVNDV DNMYTRLQAM
DSWSTVSVGL QQHTQQQVQF TRLAGNADTL PLQILAQAVE PAQYYTRQHL KFQAGNYHQF
EPLNRFADAL NAESATVRQM HKWADRLVSD AEDTESADAL RHVFNRWQSN TSDALALSEN
SYQLKAMKPV IQEVDKLASI GLRLTDLVAR QGTLDDKEIA SIQSELDNAA KVQDEVVIAA
VYPLETLLRA TRNQ
//
